The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Dose escalation stage of a first-in-class phase I study of the novel oral ERK 1/2 kinase inhibitor BVD-523 (ulixertinib) in patients with advanced solid tumors.
 
Jeffrey R. Infante
No Relationships to Disclose
 
Filip Janku
No Relationships to Disclose
 
Anthony W. Tolcher
Stock and Other Ownership Interests - Symphony Evolution
Consulting or Advisory Role - AbbVie; Adnexus; Ambit BioSciences; AP Pharma; Aragon Pharmaceuticals; ARIAD; ArQule; Asana Biosciences; Astellas Pharma; Astex Pharmaceuticals; AVID Radiopharmaceuticals; Bayer Schering Pharma; Bind Therapeutics; BioMed Valley Discoveries; Blend Therapeutics; Bristol-Myers Squibb; Celator; Clovis Oncology; Curis; Dicerna; Eisai; Emergent BioSolutions; Heron; Janssen; Johnson & Johnson; Lilly; MedImmune; Merck Sharp & Dohme; Merus; Micromet; Nanobiotix; Nektar; Neumedicines; Novartis (I); Oncogenex; Pfizer; Pharmacyclics; Pierre Fabre; ProNAi; Proximagen; Symphony Evolution; Vaccinex; Valent Technologies; Zyngenia; Zyngenia
 
Manish R. Patel
No Relationships to Disclose
 
Ryan J. Sullivan
Consulting or Advisory Role - Astex Pharmaceuticals
 
Keith Flaherty
Stock and Other Ownership Interests - Clovis Oncology; Loxo
Consulting or Advisory Role - Amgen; Genentech; GlaxoSmithKline; Lilly; Merck; Momenta Pharmaceuticals; Novartis; Oncoceutics; Sanofi; Viralytics; ZIOPHARM Oncology
Research Funding - Novartis; Sanofi
Travel, Accommodations, Expenses - GlaxoSmithKline; Sanofi
 
Richard D. Carvajal
Consulting or Advisory Role - AstraZeneca; Aurora Health Care; Novartis
Research Funding - Amgen; AstraZeneca; Aura Biosciences; Bayer; Bristol-Myers Squibb; Celldex; Daiichi Sankyo; Incyte; MedImmune; Merck; Novartis; Pfizer; Pharma Marathi; Threshold Pharmaceuticals
 
Anna M. Varghese
Research Funding - BioMed Valley Discoveries; Lilly; Taiho Pharmaceutical; Verastem
 
Deborah Jean Lee Wong
Research Funding - ARMO BioSciences; AstraZeneca; BioMed Valley Discoveries; EMD Serono; Merck; Roche/Genentech
 
Mario Sznol
Consulting or Advisory Role - Amgen; Anaeropharma; AstraZeneca/MedImmune; Bristol-Myers Squibb; Genentech/Roche; Immune Design; Kyowa Hakko Kirin; Lion Biotechnologies; Merus; Nektar; Symphony Evolution
Other Relationship - Haymarket Media
 
Jeffrey Alan Sosman
No Relationships to Disclose
 
Andrea Wang-Gillam
Consulting or Advisory Role - Merrimack; Pfizer
Research Funding - AstraZeneca; EMD Serono; Halozyme; Merrimack; Newlink Genetics; OncoMed; Pfizer; Precision Therapeutics
 
Howard A. Burris
No Relationships to Disclose
 
Antoni Ribas
Stock and Other Ownership Interests - Compugen; Kite, a Gilead company
Consulting or Advisory Role - Amgen; Genentech/Roche; GlaxoSmithKline; Merck; Novartis
Research Funding - Merck Sharp & Dohme (Inst)
 
Sapna Pradyuman Patel
Consulting or Advisory Role - Amgen; Genentech/Roche; MD Anderson Cancer Center
Speakers' Bureau - Merck
Research Funding - Bristol-Myers Squibb (Inst); Celgene (Inst); Deciphera (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Prometheus (Inst); Reata Pharmaceuticals (Inst)
 
Dean J. Welsch
Employment - BioMed Valley Discoveries
Patents, Royalties, Other Intellectual Property - BioMed Valley Discoveries
 
Saurabh Saha
Employment - BioMed Valley Discoveries
Patents, Royalties, Other Intellectual Property - BioMed Valley Discoveries