The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A first-in-human study of the dual ROCK I/II inhibitor, AT13148, in patients with advanced cancers.
 
Dionysios Papadatos-Pastos
No Relationships to Disclose
 
Rajiv Kumar
No Relationships to Disclose
 
Timothy Anthony Yap
Research Funding - AstraZeneca
 
Ruth Ruddle
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research (Inst)
 
Shaun Decordova
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research (Inst)
 
Paul Jones
No Relationships to Disclose
 
Gavin Halbert
Expert Testimony - Hospira
 
Michelle D Garrett
Consulting or Advisory Role - Astex Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research (Inst)
 
Robert McLeod
No Relationships to Disclose
 
Zoe Backholer
No Relationships to Disclose
 
Karen E Swales
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research (Inst)
 
Florence I. Raynaud
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research
 
Johann Sebastian De Bono
Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi
Research Funding - Arno Therapeutics (Inst); AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst); Tokai Pharmaceuticals (Inst)
 
Udai Banerji
Honoraria - Astex Pharmaceuticals
Consulting or Advisory Role - Astex Pharmaceuticals
Research Funding - AstraZeneca; Chugai Pharma; Lupin Pharmaceuticals; Merck; Novartis; Onyx; Synthon; Verastem
Patents, Royalties, Other Intellectual Property - Institute of Cancer Research (Inst)
Travel, Accommodations, Expenses - Astex Pharmaceuticals