The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A pharmacokinetically (PK) and pharmacodynamically (PD) driven phase I trial of the pan-AKT inhibitor AZD5363 with expansion cohorts in PIK3CA mutant breast and gynecological cancers.
 
Udai Banerji
Honoraria - Astex Pharmaceuticals
Consulting or Advisory Role - Astex Pharmaceuticals
Research Funding - AstraZeneca; Chugai Pharma; Lupin Pharmaceuticals; Merck; Novartis; Onyx; Synthon; Verastem
 
Emma Jane Dean
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Eisai (Inst); GlaxoSmithKline (Inst); Vertex (Inst)
 
Jose Alejandro Perez-Fidalgo
Consulting or Advisory Role - Teva
Speakers' Bureau - GlaxoSmithKline; Merck Sharp & Dohme; Novartis; Roche Pharma AG
 
Gerald Batist
No Relationships to Disclose
 
Philippe L. Bedard
Consulting or Advisory Role - Genentech/Roche (Inst); Pfizer (Inst); Sanofi (Inst)
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Oncothyreon (Inst); Sanofi (Inst); SERVIER (Inst); SignalChem (Inst)
 
Benoit You
No Relationships to Disclose
 
Shannon Neville Westin
Consulting or Advisory Role - OCT Group
Research Funding - AstraZeneca; Novartis
Travel, Accommodations, Expenses - AstraZeneca
 
Peter Kabos
Research Funding - AstraZeneca (Inst)
 
Barry Davies
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Paul Elvin
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Peter Lawrence
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
James W T Yates
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Helen Ambrose
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Paul Rugman
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Andrew Foxley
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Shaista Salim
Employment - AstraZeneca; Roche Pharma AG
Stock and Other Ownership Interests - Roche Pharma AG
 
Ed Casson
Employment - AstraZeneca; UCB
 
Justin P O Lindemann
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Jan H. M. Schellens
No Relationships to Disclose