The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Safety and tolerability of increasing doses of CB-839, a first-in-class, orally administered small molecule inhibitor of glutaminase, in solid tumors.
 
James J. Harding
Consulting or Advisory Role - MedImmune
Research Funding - Calithera Biosciences (Inst); Lilly (Inst); Polaris (Inst)
 
Melinda L. Telli
No Relationships to Disclose
 
Pamela N. Munster
Honoraria - Amgen (I); Threshold Pharmaceuticals
Research Funding - Bristol-Myers Squibb (Inst); Celgene (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Intellikine (Inst); Merck (Inst); Merrimack (Inst); Nektar (Inst); Novartis (Inst); OncoMed (Inst); Onconova Therapeutics (Inst); oncosec (Inst); Pfizer (Inst); Piramal Life Science (Inst); Plexxikon (Inst); Sanofi (Inst)
 
Mai H. Le
Stock and Other Ownership Interests - Calithera Biosciences
 
Christopher Molineaux
Employment - Calithera Biosciences; Calithera Biosciences (I)
Leadership - Calithera Biosciences; Calithera Biosciences (I)
Stock and Other Ownership Interests - Calithera Biosciences; Calithera Biosciences (I)
 
Mark K. Bennett
Employment - Calithera Biosciences
Stock and Other Ownership Interests - Calithera Biosciences
 
Erik Mittra
No Relationships to Disclose
 
Howard A. Burris
No Relationships to Disclose
 
Amy Sanders Clark
No Relationships to Disclose
 
Mark Dunphy
No Relationships to Disclose
 
Funda Meric-Bernstam
Honoraria - Genentech; Roche; Sysmex
Consulting or Advisory Role - Genentech; Novartis; Roche
Research Funding - AstraZeneca; Bayer; Calithera Biosciences; Debiopharm Group; Genentech; Novartis; Taiho Pharmaceutical
 
Manish R. Patel
No Relationships to Disclose
 
Angela DeMichele
Honoraria - Pfizer
Research Funding - Bayer (Inst); Calithera Biosciences (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Millennium (Inst); Pfizer (Inst); Veridex (Inst); Wyeth (Inst)
Travel, Accommodations, Expenses - Pfizer
 
Jeffrey R. Infante
Consulting or Advisory Role - Calithera Biosciences (Inst)
Research Funding - Calithera Biosciences (Inst)