The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1 dose escalation study of RXDX-105, an oral RET and BRAF inhibitor, in patients with advanced solid tumors.
 
Manish R. Patel
Honoraria - Gilead Sciences; Medivation; Taiho Pharmaceutical
Speakers' Bureau - Gilead Sciences; Medivation; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Gilead Sciences; medivation; Taiho Pharmaceutical
 
Marwan Fakih
Honoraria - Sirtex Medical
Consulting or Advisory Role - Amgen; Sirtex Medical
Speakers' Bureau - Sirtex Medical
Research Funding - Amgen (Inst); Novartis (Inst)
 
Anthony J. Olszanski
Consulting or Advisory Role - Janssen; Merck; Takeda
Research Funding - Advaxis (Inst); Amgen (Inst); EMD Serono (Inst); Ignyta (Inst); Immunocore (Inst); Incyte (Inst); Kyowa Hakko Kirin (Inst); Lilly (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Takeda (Inst); TC Biopharm (Inst)
Travel, Accommodations, Expenses - Takeda
 
Albert C. Lockhart
Research Funding - Amgen (Inst); Bayer (Inst); CTI (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Lilly (Inst); Millennium (Inst); Novartis (Inst); Regeneron (Inst); Sanofi (Inst); Teva (Inst); Vertex (Inst); Zenyaku Kogyo (Inst)
 
Alexander E. Drilon
Honoraria - Exelixis; Genentech/Roche; Ignyta
Consulting or Advisory Role - AstraZeneca; Exelixis; Genentech/Roche
Speakers' Bureau - Ignyta
Research Funding - Foundation Medicine
Travel, Accommodations, Expenses - AstraZeneca; Exelixis; Genentech/Roche; Ignyta
 
Siqing Fu
No Relationships to Disclose
 
Lyudmila Bazhenova
Stock and Other Ownership Interests - Epic Sciences
Consulting or Advisory Role - AstraZeneca; Genoptix; Heat Biologics; Pfizer
Speakers' Bureau - Genentech; Novartis
 
Rupal Patel
Employment - Ignyta
 
Jennifer W. Oliver
Employment - Ignyta; MEI Pharma
Stock and Other Ownership Interests - Ignyta
Consulting or Advisory Role - Clovis Oncology
Research Funding - Ignyta
 
Pratik S. Multani
Employment - Fate Therapeutics; Ignyta
Leadership - Fate Therapeutics; Ignyta
Stock and Other Ownership Interests - Fate Therapeutics; Ignyta
Consulting or Advisory Role - Fate Therapeutics
 
Ding Wang
No Relationships to Disclose