The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase I pharmacokinetic study of single agent trametinib in advanced cancer patients with hepatic dysfunction: An NCI Organ Dysfunction Working Group (ODWG) study.
 
Anna Spreafico
No Relationships to Disclose
 
Eric Chen
No Relationships to Disclose
 
Solmaz Sahebjam
Research Funding - Cortice Biosciences; Merck
 
Daniel John Renouf
Honoraria - Amgen; Celgene
Consulting or Advisory Role - Celgene
 
Karen Kelly
Honoraria - Bristol-Myers Squibb; Roche
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Lilly; Synta
Research Funding - Abbvie (Inst); Celgene (Inst); EMD Serono (Inst); Genentech (Inst); Gilead Sciences (Inst); Lilly (Inst); Millennium (Inst); Novartis (Inst); Synta (Inst)
Patents, Royalties, Other Intellectual Property - Author Royalties for UpToDate, an evidence based, peer reviewed information resource, available via the web, desktop, and PDA.
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; Clovis Oncology; Lilly; Roche; Synta
 
Albert C. Lockhart
Research Funding - Amgen (Inst); Bayer (Inst); CTI (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Lilly (Inst); Millennium (Inst); Novartis (Inst); Regeneron (Inst); Sanofi (Inst); Teva (Inst); Vertex (Inst); Zenyaku Kogyo (Inst)
 
Ulka N. Vaishampayan
Honoraria - Astellas Pharma; Bayer; Janssen; Novartis; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Novartis; Pfizer; Sanofi
Speakers' Bureau - Astellas Pharma; Bayer; Janssen; Novartis; Pfizer
Research Funding - Astellas Pharma; Exelixis; Novartis; Pfizer
 
Sebastien J. Hotte
No Relationships to Disclose
 
Albiruni R. Razak
No Relationships to Disclose
 
Lisa Wang
No Relationships to Disclose
 
Lee-Anne Stayner
No Relationships to Disclose
 
Alanna Bougie
No Relationships to Disclose
 
Helen X. Chen
No Relationships to Disclose
 
S. Percy Ivy
No Relationships to Disclose
 
Lillian L. Siu
Leadership - Agios (I)
Stock and Other Ownership Interests - Agios (I); Entremed (I)
Consulting or Advisory Role - Boehringer Ingelheim; Daiichi Sankyo; Merck; Novartis (Inst); Oncoethix
Research Funding - Abraxis BioScience; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Celgene; Genentech/Roche; GlaxoSmithKline; Karyopharm Therapeutics; MedImmune; Merck; Novartis; Pfizer; Regeneron