The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies.
 
David R. Spigel
Stock and Other Ownership Interests - Foundation Medicine; Illumina
Consulting or Advisory Role - AstraZeneca; Biodesix; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Clovis Oncology; Genentech/Roche; Lilly; Novartis; Pfizer
Speakers' Bureau - Novartis
Research Funding - Amgen (Inst); Astex Pharmaceuticals (Inst); AstraZeneca (Inst); BIND Biosciences (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Clovis Oncology (Inst); CytRx Corporation (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Genentech/Roche (Inst); ImClone Systems (Inst); Immunogen (Inst); Lilly (Inst); Novartis (Inst); Oncogenex (Inst); OncoMed (Inst); Peregrine Pharmaceuticals (Inst); Pfizer (Inst); University of Texas Southwestern Medical Center - Simmons Cancer Center (Inst); Verastem (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Biodesix; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Clovis Oncology; Genentech/Roche; Lilly; Novartis; Pfizer
 
Alexa Betzig Schrock
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
David Fabrizio
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Garrett Michael Frampton
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
James Sun
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Jie He
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Kyle Gowen
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Melissa Lynne Johnson
Honoraria - Genentech
Consulting or Advisory Role - Astellas Pharma (I); Otsuka (I)
Research Funding - Novartis
 
Todd Michael Bauer
No Relationships to Disclose
 
Gregory Peter Kalemkerian
Consulting or Advisory Role - BioMed Valley Discoveries (I); Esperion Therapeutics (I); Millennium (I)
Research Funding - Astex Pharmaceuticals (Inst); GlaxoSmithKline (Inst); Merck (Inst); Millennium (Inst); OncoMed (Inst)
 
Luis E. Raez
Research Funding - Boehringer Ingelheim (Inst); Genentech/Roche (Inst); Merck Serono (Inst); Novartis (Inst); Pfizer (Inst)
 
Sai-Hong Ignatius Ou
Honoraria - Pfizer; Roche Pharma AG
Consulting or Advisory Role - Pfizer; Roche/Genentech
Speakers' Bureau - Boehringer Ingelheim; Genentech
Research Funding - ARIAD (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); AstraZeneca/MedImmune (Inst); Chugai Pharma (Inst); Clovis Oncology (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Peregrine Pharmaceuticals (Inst); Pfizer (Inst); Roche Pharma AG (Inst)
 
Jeffrey S. Ross
Employment - Foundation Medicine
Leadership - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
Honoraria - Bristol-Myers Squibb; Genentech/Roche; Pfizer
Research Funding - Foundation Medicine
 
Philip J. Stephens
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Vincent A. Miller
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Siraj Mahamed Ali
Employment - Foundation Medicine
Honoraria - Foundation Medicine