The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase I trial of a first-in-class ATR inhibitor VX-970 as monotherapy (mono) or in combination (combo) with carboplatin (CP) incorporating pharmacodynamics (PD) studies.
 
Brent O'Carrigan
No Relationships to Disclose
 
Maria Jose de Miguel Luken
No Relationships to Disclose
 
Dionysios Papadatos-Pastos
No Relationships to Disclose
 
Jessica Brown
No Relationships to Disclose
 
Nina Tunariu
No Relationships to Disclose
 
Raquel Perez Lopez
No Relationships to Disclose
 
Mahesha Ganegoda
No Relationships to Disclose
 
Ruth Riisnaes
No Relationships to Disclose
 
Ines Figueiredo
No Relationships to Disclose
 
Suzanne Carreira
No Relationships to Disclose
 
Brian Hare
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
Fang Yang
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
Katherine McDermott
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
Marina S. Penney
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
John Pollard
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
Juanita Suzanne Lopez
No Relationships to Disclose
 
Udai Banerji
No Relationships to Disclose
 
Johann S. De Bono
Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi
Research Funding - AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); PARP inhibitors and DNA repair defects (Inst)
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex
 
Scott Z. Fields
Employment - Vertex
Stock and Other Ownership Interests - Vertex
 
Timothy Anthony Yap
Consulting or Advisory Role - Pfizer
Research Funding - AstraZeneca; Clearbridge Biomedics; Vertex
Travel, Accommodations, Expenses - Janssen-Cilag; MSD Oncology; Vertex