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GEOMETRY duo-1: A phase (Ph) Ib/II, multicenter trial of oral cMET inhibitor capmatinib (INC280) ± erlotinib vs platinum + pemetrexed in adult patients (pts) with epidermal growth factor receptor (EGFR)-mutated, cMET-amplified, locally advanced/metastatic non-small cell lung cancer (NSCLC) with acquired resistance to prior EGFR tyrosine kinase inhibitor (TKI) therapy. |
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Consulting or Advisory Role - Lilly |
Research Funding - AstraZeneca (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Roche/Genentech (Inst) |
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Consulting or Advisory Role - Bristol-Myers Squibb; MSD; Sanofi |
Expert Testimony - GlaxoSmithKline; LEO Pharma; Novartis; Pfizer |
Travel, Accommodations, Expenses - Amgen; Lilly; Novartis; Sanofi |
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No Relationships to Disclose |
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Travel, Accommodations, Expenses - Celgene; Merck |
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Honoraria - Novartis; Roche |
Research Funding - Astellas Pharma; AstraZeneca; Boehringer Ingelheim; Clovis Oncology; MedImmune; Roche |
Expert Testimony - Novartis |
Travel, Accommodations, Expenses - Roche |
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No Relationships to Disclose |
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Consulting or Advisory Role - Boehringer Ingelheim; Bristol-Myers Squibb; Novartis; Pfizer; Samsung |
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Consulting or Advisory Role - Boehringer Ingelheim; Lilly; Pfizer; Roche |
Speakers' Bureau - Boehringer Ingelheim; Pfizer |
Research Funding - Boehringer Ingelheim |
Expert Testimony - Boehringer Ingelheim; Pfizer |
Travel, Accommodations, Expenses - Boehringer Ingelheim; Pfizer; Roche |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Novartis |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Novartis |
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Honoraria - Novartis; Pfizer |
Consulting or Advisory Role - Bayer; Boehringer Ingelheim; Novartis |
Research Funding - Bayer; GlaxoSmithKline; Novartis |
Travel, Accommodations, Expenses - Merck; Novartis |