The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E (ASG-15ME) in a phase I dose escalation trial in patients (Pts) with metastatic urothelial cancer (mUC).
 
Daniel Peter Petrylak
Stock and Other Ownership Interests - Bellicum Pharmaceuticals; TYME
Honoraria - Astellas Pharma; Bayer; Bellicum Pharmaceuticals; Exelixis; Ferring; Genentech; Johnson & Johnson; Medivation; Merck Serono; Millennium; Pfizer; Progenics; Sanofi
Consulting or Advisory Role - Bayer; Bellicum Pharmaceuticals; Dendreon; Exelixis; Ferring; Johnson & Johnson; Medivation; Millennium; Pfizer; Sanofi
Research Funding - Astellas Medivation; Dendreon; Endocyte; Genentech; gtx; Johnson & Johnson; Merck; Millennium; Novartis; Oncogenex; Progenics; progenics; Sanofi
Expert Testimony - Celgene; sanofi
Travel, Accommodations, Expenses - Bayer; Bellicum Pharmaceuticals; Celgene; Dendreon; Exelixis; Ferring; Johnson & Johnson; Medivation; Millennium; Oncogenex; Pfizer; Progenics; Sanofi
 
Elisabeth I. Heath
Honoraria - Bayer; Dendreon; Sanofi
Consulting or Advisory Role - Agensys
Research Funding - Agensys (Inst); Celgene (Inst); Celldex (Inst); Dendreon (Inst); Genentech/Roche (Inst); Inovio Pharmaceuticals (Inst); Millennium (Inst); Seagen (Inst); Tokai Pharmaceuticals (Inst)
 
Guru Sonpavde
Consulting or Advisory Role - Agensys; Argos Therapeutics; Bayer; Genentech; Merck; Novartis; Pfizer; Sanofi
Research Funding - Bayer (Inst); Boehringer Ingelheim (Inst); Onyx (Inst)
 
Saby George
Employment - Amgen (I)
Consulting or Advisory Role - Astellas Pharma; Bayer; Bristol-Myers Squibb; Novartis; Onclive; Pfizer; Xcenda
Research Funding - Acceleron Pharma (Inst); Agensys (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst)
 
Alicia Katherine Morgans
Consulting or Advisory Role - Dendreon; Myriad Genetics
Travel, Accommodations, Expenses - Dendreon; Myriad Genetics
 
Bernhard J. Eigl
No Relationships to Disclose
 
Joel Picus
Consulting or Advisory Role - Novo Nordisk
Research Funding - Agensys; Altor BioScience; Astex Pharmaceuticals; BioClin Therapeutics; Mirati Therapeutics; Novartis; Oncogenex
 
Susanna Y. Cheng
Honoraria - Roche/Genentech
Consulting or Advisory Role - Boehringer Ingelheim; Roche/Genentech
Speakers' Bureau - Peerview
 
Sebastien J. Hotte
Honoraria - Astellas Scientific and Medical Affairs Inc; Janssen Oncology; Sanofi
Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Janssen
Research Funding - Agensys; AstraZeneca; Bayer; Boehringer Ingelheim; Novartis; Oncogenex; Roche/Genentech; Sanofi
 
Elaina M. Gartner
Employment - Seagen
Stock and Other Ownership Interests - Seagen
 
Martha Vincent
Employment - Agensys
Stock and Other Ownership Interests - Amgen; Pfizer
 
Rong Chu
Employment - Agensys
Stock and Other Ownership Interests - Amgen; Gilead Sciences; Vertex
 
Banmeet Anand
Employment - Agensys
 
Karen Morrison
Employment - Agensys
Patents, Royalties, Other Intellectual Property - Agensys (Inst)
 
Lynnae Jackson
Employment - Agensys
 
Leonard M. Reyno
Employment - Agensys
 
Evan Y. Yu
Consulting or Advisory Role - Agensys; Bayer; Dendreon; Ferring; Genentech/Roche; Janssen; Medivation; Merck; Sanofi; Seagen; Tokai Pharmaceuticals; Tolmar
Research Funding - Agensys (Inst); Astellas Pharma (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Dendreon (Inst); Genentech/Roche (Inst); GTx (Inst); Lilly/ImClone; Oncogenex (Inst)
Travel, Accommodations, Expenses - Exelixis; Lilly