The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A first-in-human phase 1 study to evaluate the brain-penetrant PI3K/mTOR inhibitor GDC-0084 in patients with progressive or recurrent high-grade glioma.
 
Patrick Y. Wen
Consulting or Advisory Role - AbbVie; Agios; Angiochem; AstraZeneca; Cavion; Celldex; Exelixis; Genentech/Roche; GlaxoSmithKline; Karyopharm Therapeutics; Midatech Pharma; Momenta Pharmaceuticals; Novartis; Novocure; Regeneron; Sanofi; Sigma-Tau; Vascular Biogenics
Speakers' Bureau - Merck
 
Timothy Francis Cloughesy
Consulting or Advisory Role - Abbvie; Agios; Amgen; Celgene; Celldex; cortice; CytRx Corporation; Lpath; Nektar; NewGen Therapeutics; Novartis; Novocure; Oxigene; proximagen; Roche/Genentech; Stemcycle; Tocagen; Upsher-Smith; VBL Therapeutics; wellcome trust
 
Alan Olivero
Employment - Genentech
Leadership - Genentech
Stock and Other Ownership Interests - Genentech
Research Funding - Genentech
Patents, Royalties, Other Intellectual Property - Genentech
 
Xuyang Lu
Employment - Genentech
Stock and Other Ownership Interests - Genentech
 
Lars Mueller
Employment - Genentech
Stock and Other Ownership Interests - Genentech
 
Alexandre Fernandez Coimbra
Employment - Genentech
Stock and Other Ownership Interests - Genentech
 
Elizabeth Robins Gerstner
No Relationships to Disclose
 
Jordi Rodon Ahnert
Consulting or Advisory Role - Lilly/ImClone; Novartis; SERVIER