The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Updated overall survival (OS) analysis of NAPOLI-1: Phase 3 study of nanoliposomal irinotecan (nal-IRI, MM-398), with or without 5-fluorouracil and leucovorin (5-FU/LV), vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine (gem)-based therapy.
 
Andrea Wang-Gillam
Honoraria - Merrimack; Pfizer
Consulting or Advisory Role - Merrimack; pfizer
Research Funding - Aduro Biotech (Inst); AstraZeneca (Inst); CTI (Inst); EMD Serono (Inst); Halozyme (Inst); Merrimack (Inst); Newlink Genetics (Inst); OncoMed (Inst); pfizer (Inst); Precision Therapeutics (Inst); Prometheus (Inst)
Travel, Accommodations, Expenses - Axis Pharma
 
Chung-Pin Li
No Relationships to Disclose
 
Gyorgy Bodoky
No Relationships to Disclose
 
Andrew Dean
Consulting or Advisory Role - AstraZeneca; Roche; Specialised Therapeutics
Travel, Accommodations, Expenses - Boehringer Ingelheim; Roche
 
Yang-Shen Shan
No Relationships to Disclose
 
Gayle S. Jameson
Research Funding - Merrimack
 
Teresa Macarulla
No Relationships to Disclose
 
Kyung-Hun Lee
No Relationships to Disclose
 
David Cunningham
Research Funding - Amgen (Inst); AstraZeneca (Inst); Celgene (Inst); MedImmune (Inst); Merck Serono (Inst); Merrimack (Inst); Sanofi (Inst)
 
Jean-Frédéric Blanc
No Relationships to Disclose
 
Richard Hubner
No Relationships to Disclose
 
Chang-Fang Chiu
No Relationships to Disclose
 
Gilberto Schwartsmann
No Relationships to Disclose
 
Jens T Siveke
Consulting or Advisory Role - Merrimack
 
Fadi S. Braiteh
Consulting or Advisory Role - Merrimack
 
Victor M. Moyo
Employment - Merrimack
Stock and Other Ownership Interests - Merrimack
Patents, Royalties, Other Intellectual Property - Merrimack
 
Bruce Belanger
Employment - Merrimack
 
Eliel Bayever
Employment - Merrimack
Patents, Royalties, Other Intellectual Property - Merrimack
 
Daniel D. Von Hoff
Employment - McKesson
Stock and Other Ownership Interests - Cell Therapeutics; CerRx; EmergingMed; McKesson; Medtronic; SynDevRx
Honoraria - Celgene; Cerulean Pharma; Genentech
Consulting or Advisory Role - AADi; Alethia Biotherapeutics; Alpha Cancer Technologies; Aptose Biosciences; Arsia Therapeutics; Arvinas; Bellicum Pharmaceuticals; BiolineRx; Biological Dynamics; Bionomics; Bristol-Myers Squibb; CanBas; Cavion; Cerulean Pharma; CV6 Therapeutics ; CytomX Therapeutics; CytRx Corporation; dalian wanchun biotechnology; Deciphera; DNAtrix; EMD Serono; Esperance Pharmaceuticals; Evelo Therapeutics; Five Prime Therapeutics; Formula Pharmaceuticals; Fujifilm; Gilead Sciences; HealthCare Pharmaceuticals; Histogen; Horizon Discovery; Horizon Pharma; Idera; Ignyta; Imaging Endpoints; Immodulon Therapeutics; Inform Genomics; Innate Pharma; Insys Therapeutics; Intezyne Technologies; Kalos Therapeutics; Kinex; Kura Oncology; Lantern Pharma; Lilly; Lixte Biotechnology; MBC Pharma; Medelis; Medical Prognosis Institute; Merus; miRNA Therapeutics; Nucana; Oncolytics; Oncolyze; Pain Therapeutics; Pain Therapeutics; Pfizer; Pharmacyclics; Pharmamab; Phosplatin Therapeutics; Progen; RenovoRx; Samsung; Samumed; Senhwa Biosciences; SOTIO; Strategia Therapeutics; Sun Biopharma; Superlab Far East; Synergene; Systems Imagination; TD2; Theravance; Tolero Pharmaceuticals; Toray Industries; Trovagene; Ventana Medical Systems
Research Funding - 3-V Biosciences (Inst); Abbvie (Inst); Aduro Biotech (Inst); Agios (Inst); ArQule (Inst); Baxalta (Inst); Biomarin (Inst); Celgene (Inst); Cleave Biosciences (Inst); CytRx Corporation (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); Endocyte (Inst); ESSA (Inst); Exelixis (Inst); Five Prime Therapeutics (Inst); Genentech (Inst); Gilead Sciences (Inst); Incyte (Inst); Lilly (Inst); Merck (Inst); Merrimack (Inst); Minneamrita Therapeutics (Inst); miRNA Therapeutics (Inst); Pfizer (Inst); Pharmacyclics (Inst); Phoenix Biotech (Inst); Plexxikon (Inst); Proderm IQ (Inst); Samumed (Inst); Strategia (Inst); Trovagene (Inst); Verastem (Inst)
Patents, Royalties, Other Intellectual Property - 2-aryl-pyridylazoles for the Treatment of Solid Tumors such as Pancreatic Cancer (pending); Intramedullary Catheter; Methods and Kits to Predict Therapeutic Outcome of BTK Inhibitors (pending); Methods of Human Prostate Cancer; Methods, Compounds and Compositions with Genotype Selective Anticancer Activity (pending); Muscle Fatigue Substance Cytokines and Methods of Inhibiting Tumor Growth Therewith (pending); Protein Kinase Inhibitors (pending); Targeting a Protein PRC1 for the Treatment of Pancreatic Cancer (pending); Targeting a Protein Tyrosine Phosphotase-PRL-1 for the Treatment of Pancreatic Cancer (pending); Targeting Ecto-5-Nucleotidase (Cd73) for the Treatment of Pancreatic Cancer; Targeting Ecto-5-Nucleotidase (CD73) for the Treatment of Pancreatic Cancer (pending); Targeting Site-2 Protease (S2P) for the Treatment of Pancreatic Cancer (pending); Use of 5,6-Dihydro-5-Azacytidine in the Treatment of Prostate Cancer
Travel, Accommodations, Expenses - FORMA Therapeutics; Merrimack
 
Li-Tzong Chen
Honoraria - PharmaEngine
Consulting or Advisory Role - PharmaEngine
Other Relationship - Merrimack