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A prospective, multicenter, randomized clinical trial of UGT1A1 promoter polymorphism for irinotecan dose escalation in metastatic colorectal cancer patients treated with bevacizumab plus FOLFIRI as the first-line setting (PURE FIST).

Jaw-Yuan  Wang

Consulting or Advisory Role - Bayer

Speakers' Bureau - Bayer; Merck; Pfizer; Roche

Research Funding - Roche