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Updated efficacy, safety, and biomarker analyses of STEAM, a randomized, open-label, phase II trial of sequential (s) and concurrent (c) FOLFOXIRI-bevacizumab (BV) vs FOLFOX-BV for first-line (1L) treatment (tx) of patients with metastatic colorectal cancer (mCRC). |
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Honoraria - Genentech/Roche; Lilly/ImClone |
Consulting or Advisory Role - Acceleron Pharma; Bristol-Myers Squibb; Genentech/Roche; GlaxoSmithKline; Incyte; Lilly; Novartis; OncoMed; TRACON Pharma |
Research Funding - Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Macrogenics (Inst); NCI (Inst); Novartis (Inst); Regeneron (Inst); TRACON Pharma (Inst) |
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Consulting or Advisory Role - Roche/Genentech |
Research Funding - Bayer; Boehringer Ingelheim; Eisai; Exelixis; Lilly; Merck Serono; Pfizer; Roche/Genentech; Sillajen; tyrogenex |
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Speakers' Bureau - Celgene |
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No Relationships to Disclose |
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Research Funding - Alaxo; Exelixis; Genentech; GlaxoSmithKline; Lilly; Merck; Millennium; Novartis |
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Honoraria - Bayer; Boehringer Ingelheim; Merck Serono; Roche |
Consulting or Advisory Role - Bayer; Merck Serono; Roche |
Travel, Accommodations, Expenses - Bayer; Merck Serono; Roche |
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Consulting or Advisory Role - Amgen; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech; Sirtex Medical |
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Stock and Other Ownership Interests - Genentech |
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Stock and Other Ownership Interests - Roche |
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Stock and Other Ownership Interests - Roche |
Patents, Royalties, Other Intellectual Property - Roche |
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Travel, Accommodations, Expenses - Roche |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Research Funding - Apexigen (Inst); Array BioPharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Kolltan Pharmaceuticals (Inst); Leap Therapeutics (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Oncogenex (Inst); OncoMed (Inst); SynDevRx (Inst); Taiho Pharmaceutical (Inst) |