The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase I study of AG-120, an IDH1 mutant enzyme inhibitor: Results from the cholangiocarcinoma dose escalation and expansion cohorts.
 
Maeve Aine Lowery
Consulting or Advisory Role - Agios; Celgene
 
Ghassan K. Abou-Alfa
Consulting or Advisory Role - Aduro Biotech (I); Agios; Array BioPharma (I); ASLAN Pharmaceuticals; Astellas Pharma; AstraZeneca; Bayer; Blueprint Medicines; Boston Scientific; Bristol-Myers Squibb (I); CASI Pharmaceuticals; Celgene; Celgene (I); Celsion; Delcath Systems; Eisai; EMD Serono (I); Gilead Sciences (I); Halozyme (I); IntegraGen; Ipsen; Janssen (I); Medimmune; Merck Serono; Merrimack; Merrimack (I); Momenta Pharmaceuticals (I); New B Innovation; Newlink Genetics (I); Onxeo; Opsona Therapeutics (I); Pfizer (I); Roche; Sanofi (I); SERVIER; Silenseed (I); Sillajen; Sirtex Medical; VAXIMM (I); Vicus Therapeutics; Vicus Therapeutics (I); Westhaven
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); CASI Pharmaceuticals (Inst); Chugai Pharma (Inst); Exelixis (Inst); Genentech (Inst); Incyte (Inst); MabVax (Inst); MedImmune (Inst); Momenta Pharmaceuticals (Inst); OncoMed (Inst); Polaris (Inst); Roche (Inst); Vicus Therapeutics (Inst)
Travel, Accommodations, Expenses - Polaris
 
Howard A. Burris
No Relationships to Disclose
 
Filip Janku
Consulting or Advisory Role - Deciphera; Foundation Medicine; Guardant Health; Novartis; Sequenom; Trovagene
Research Funding - Agios; Astellas Pharma; Biocartis; BioMed Valley Discoveries; Deciphera; Foundation Medicine; Fujifilm; Novartis; Piqur; Plexxikon; Roche; Symphony Evolution; Trovagene
Other Relationship - Bio-Rad
 
Rachna T. Shroff
Stock and Other Ownership Interests - Celgene
Consulting or Advisory Role - Agios; Amgen; Celgene; Clovis Oncology; Codiak Biosciences
Research Funding - Agios; Celgene; Lilly
Travel, Accommodations, Expenses - Amgen; Celgene; Codiak Biosciences
 
James M. Cleary
No Relationships to Disclose
 
Nilofer Saba Azad
Honoraria - Bayer/Onyx
Consulting or Advisory Role - Dava Oncology
Research Funding - Agios (Inst); Astex Pharmaceuticals (Inst); Celgene (Inst); Genentech (Inst); Kinex (Inst); Precision Biologics (Inst)
 
Lipika Goyal
Honoraria - Ribon Therapeutics
Research Funding - Dicerna; Exelixis; Leap Therapeutics; Taiho Pharmaceutical
 
Elizabeth A. Maher
Honoraria - Lilly
Consulting or Advisory Role - Agios
Travel, Accommodations, Expenses - Agios; Lilly
 
Lia Gore
Employment - ARIAD (I)
Leadership - ARIAD (I)
Stock and Other Ownership Interests - Amgen; ARIAD; ARIAD (I); Celgene; Clovis Oncology; Sanofi
Honoraria - Amgen
Consulting or Advisory Role - Celgene; Celgene; Genentech/Roche; GlaxoSmithKline; Jazz Pharmaceuticals; MedImmune; Meryx Pharmaceuticals; Novartis; ProEd; Spectrum Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Patent held for diagnostic discovery and treatment response methodology tools in the use of MR spectroscopy for leukemia.
Travel, Accommodations, Expenses - Amgen; GlaxoSmithKline
 
Antoine Hollebecque
Consulting or Advisory Role - Amgen
 
Muralidhar Beeram
Research Funding - The START Center for Cancer Care (Inst)
 
Jonathan C. Trent
No Relationships to Disclose
 
Liewen Jiang
Employment - Agios
Stock and Other Ownership Interests - Alexion Pharmaceuticals
 
Yuko Ishii
Employment - Agios
Stock and Other Ownership Interests - Agios
Patents, Royalties, Other Intellectual Property - Takeda
Travel, Accommodations, Expenses - Agios
 
Julia Auer
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Camelia Gliser
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Samuel V. Agresta
Employment - Agios
Stock and Other Ownership Interests - Agios
Patents, Royalties, Other Intellectual Property - Agios
 
Shuchi Sumant Pandya
Employment - Acceleron Pharma; Agios
Stock and Other Ownership Interests - Acceleron Pharma; Agios
Research Funding - Acceleron Pharma; Agios
Travel, Accommodations, Expenses - Acceleron Pharma; Agios
 
Andrew X. Zhu
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Eisai; Merck; Novartis; Sanofi
Research Funding - Bayer (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst)