The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Dose escalation results from a first-in-human, phase 1 study of the glucocorticoid-induced TNF receptor-related protein (GITR) agonist AMG 228 in patients (Pts) with advanced solid tumors.
 
Ben Tran
Honoraria - Amgen; Astellas Pharma; Bayer; Janssen; Sanofi
Consulting or Advisory Role - Amgen; Astellas Pharma; Bayer; Bristol-Myers Squibb; Ipsen; Janssen; Sanofi; SERVIER; Tolmar
Research Funding - Amgen; Astellas Pharma; AstraZeneca; Janssen; Tolmar
 
Richard D. Carvajal
Consulting or Advisory Role - AstraZeneca; Aura Biosciences; Bristol-Myers Squibb; Cesca Therapeutics; Iconic Therapeutics; Iconic Therapeutics; Immunocore; Janssen; Merck; Novartis; Regeneron; Roche/Genentech
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bayer (Inst); Genentech (Inst); Genentech/Roche (Inst); Immunocore (Inst); Incyte (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Plexxikon (Inst); Regeneron (Inst)
 
Aurelien Marabelle
Honoraria - Bristol-Myers Squibb; Genentech; Merck; Roche
Consulting or Advisory Role - Amgen; Genentech; Novartis; Roche
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Merck; Roche
Research Funding - Merus (Inst)
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb; Roche
 
Sandip P. Patel
Honoraria - Lilly; Novartis
Consulting or Advisory Role - Lilly; Novartis
Speakers' Bureau - Boehringer Ingelheim; Merck
Research Funding - Bristol-Myers Squibb; Lilly; MedImmune; Pfizer; Roche/Genentech; Xcovery
 
Patricia LoRusso
Leadership - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech/Roche; Novartis
Honoraria - Genentech/Roche
Consulting or Advisory Role - Alexion Pharmaceuticals; Astellas Pharma; Astex Pharmaceuticals; Boehringer Ingelheim; Genentech; Novartis; Pfizer
Speakers' Bureau - Genentech
Research Funding - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech (Inst); Immunogen (Inst); Merrimack (Inst); Novartis (Inst); Pfizer; Taiho Pharmaceutical (Inst); Tensha Therapeutics (Inst)
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Genentech/Roche
 
Erik Rasmussen
Employment - Amgen
Stock and Other Ownership Interests - Amgen
Travel, Accommodations, Expenses - Amgen
 
Gloria Juan
Employment - Amgen
Stock and Other Ownership Interests - Amgen
Research Funding - Amgen
 
Vijay V. Upreti
Employment - Amgen
Stock and Other Ownership Interests - Amgen
 
Gataree Ngarmchamnanrith
Employment - Amgen
Stock and Other Ownership Interests - Amgen
 
Patrick Schöffski
No Relationships to Disclose