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Phase 1 study of the p53-MDM2 inhibitor AMG 232 combined with trametinib plus dabrafenib or trametinib in patients (Pts) with TP53 wild type (TP53WT) metastatic cutaneous melanoma (MCM). |
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No Relationships to Disclose |
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Honoraria - Amgen; Bristol-Myers Squibb; Merck |
Consulting or Advisory Role - Amgen |
Speakers' Bureau - Bristol-Myers Squibb; Merck |
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No Relationships to Disclose |
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Consulting or Advisory Role - ACI Clinical; Amgen; Biodesix; Novartis; Prometheus; Takeda; WorldCare Clinical, LLC |
Research Funding - Amgen; BioMed Valley Discoveries; Deciphera; Lilly; Merck; Prometheus; Roche/Genentech |
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Consulting or Advisory Role - Bristol-Myers Squibb; Genoptix |
Research Funding - Incyte |
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Stock and Other Ownership Interests - Amgen |
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Stock and Other Ownership Interests - Amgen |
Travel, Accommodations, Expenses - Amgen |
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No Relationships to Disclose |
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Honoraria - Bristol-Myers Squibb; Merck; Roche |
Consulting or Advisory Role - Amgen; Array BioPharma; Bristol-Myers Squibb; MERCK; Novartis; Pierre Fabre; Roche/Genentech |
Travel, Accommodations, Expenses - Merck Sharp & Dohme; Roche/Genentech |