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Dose escalation results of a phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in patients (Pts) with relapsed/refractory (r/r) acute myeloid leukemia (AML). |
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Consulting or Advisory Role - Amgen; Celator/Jazz; Celgene; Daiichi Sankyo; ImmunoGen; Incyte; Millennium; Novartis; Ono Pharmaceutical; Pfizer; Seagen; Sunesis Pharmaceuticals; Takeda |
Speakers' Bureau - Celgene; Incyte; Novartis |
Research Funding - Agios; Amgen; Astellas Pharma; Celator; Daiichi Sankyo; ImmunoGen; Janssen; Juno Therapeutics; Millennium; Seagen |
Other Relationship - Celgene; GlycoMimetics |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Medtronic |
Consulting or Advisory Role - Alexion Pharmaceuticals; Amgen; ARIAD; Incyte; Pfizer |
Research Funding - Amgen; FORMA Therapeutics; Incyte; Janssen |
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Stock and Other Ownership Interests - Amgen |
Patents, Royalties, Other Intellectual Property - Amgen |
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Stock and Other Ownership Interests - Amgen |
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Stock and Other Ownership Interests - Amgen |
Travel, Accommodations, Expenses - Amgen |
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No Relationships to Disclose |
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Consulting or Advisory Role - Amgen; Daiichi Sankyo; Seagen; Sigma-Tau; Spectrum Pharmaceuticals |
Speakers' Bureau - Incyte |
Research Funding - Immunogen (Inst) |