The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase I study (BLOOM) of AZD3759, a BBB penetrable EGFR inhibitor, in EGFRm NSCLC patients with leptomeningeal metastasis (LM) who progressed after other anti-cancer therapy.
 
Byoung Chul Cho
Honoraria - AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; MSD; Novartis; Roche; Yuhan
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; MSD; Novartis; Roche; Yuhan
Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb; MSD; Novartis
Research Funding - AstraZeneca; Bayer; Novartis; Yuhan
 
Myung-Ju Ahn
Honoraria - AstraZeneca; Boehringer Ingelheim; Lilly; MSD
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Lilly; MSD
 
Jong-Seok Lee
No Relationships to Disclose
 
Dong-Wan Kim
No Relationships to Disclose
 
Sang-We Kim
No Relationships to Disclose
 
Tom John
Honoraria - AstraZeneca/MedImmune; Bristol-Myers Squibb; Lilly; Pfizer; Roche
Consulting or Advisory Role - AstraZeneca; AstraZeneca/MedImmune; Pfizer; Roche/Genentech
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Roche
 
Stephen Chuan-Hao Kao
Honoraria - AstraZeneca; Pfizer; Roche
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Roche
 
Jonathan Wade Goldman
Consulting or Advisory Role - Amgen; AstraZeneca; Bristol-Myers Squibb; Clovis Oncology; Genentech/Roche; Lilly; Trovagene; Vortex Biosciences
Research Funding - Abbvie; Array BioPharma; Astellas Pharma; Astex Pharmaceuticals; AstraZeneca/MedImmune; Bristol-Myers Squibb; Celgene; Clovis Oncology; Corvus Pharmaceuticals; Genentech/Roche; Lilly; Threshold Pharmaceuticals
 
Wu-Chou Su
No Relationships to Disclose
 
Ronald B. Natale
Employment - AstraZeneca
Consulting or Advisory Role - AstraZeneca; Lilly
Speakers' Bureau - AstraZeneca; Celerant; Lilly; Pfizer
 
Jin Seok Ahn
Honoraria - Bristol-Myers Squibb; Eisai; Janssen; Roche
Consulting or Advisory Role - Boehringer Ingelheim; Menarini
 
HyeRyun Kim
No Relationships to Disclose
 
Tae Min Kim
No Relationships to Disclose
 
Chia-Chi Lin
No Relationships to Disclose
 
Philip Overend
Employment - GlaxoSmithKline; MSD (I)
Stock and Other Ownership Interests - GlaxoSmithKline; GlaxoSmithKline (I)
 
Zhenfan Yang
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
James Chih-Hsin Yang
Honoraria - AstraZeneca; Boehringer Ingelheim; Chugai Pharma; MSD; Novartis; Roche
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; AstraZeneca (Inst); Bayer; Boehringer Ingelheim; Boehringer Ingelheim (Inst); Bristol-Myers Squibb; Celgene; Clovis Oncology; Lilly; Merck Serono; MSD Oncology; Novartis; Ono Pharmaceutical; Pfizer; Roche/Genentech; Yuhan