The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
Pharmaco-kinetics/dynamics (PK/PD) evaluation and individual patient cross-over studies with growth trajectory assessment to adaptively develop ilorasertib.
 
Michael L. Maitland
Consulting or Advisory Role - Bayer (I); Gilead Sciences (I); Merck Sharp & Dohme (I)
 
Manish Sharma
Consulting or Advisory Role - Bayer; EMD Serono; Ipsen
 
Binsheng Zhao
No Relationships to Disclose
 
Mark D. McKee
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
 
Sanja Karovic
No Relationships to Disclose
 
Vasiliki Thomeas
No Relationships to Disclose
 
Malcom McIver
No Relationships to Disclose
 
Hao Yang
No Relationships to Disclose
 
Sarina Anne Piha-Paul
No Relationships to Disclose
 
Gerald Steven Falchook
Employment - HealthONE; Sarah Cannon Research Institute
Research Funding - 3-V Biosciences; Abbvie; Aileron Therapeutics; ARMO BioSciences; AstraZeneca; Biothera; Celgene; Curegenix; Curis; DelMar Pharmaceuticals; eFFECTOR Therapeutics; EMD Serono; Fujifilm; Genmab; GlaxoSmithKline; Hutchison MediPharma; Incyte; Jounce Therapeutics; Kolltan Pharmaceuticals; Lilly; MedImmune; Millennium; Novartis; OncoMed; Precision Oncology; Regeneron; Strategia Therapeutics; Syndax; Taiho Pharmaceutical; Tesaro; Vegenics
Patents, Royalties, Other Intellectual Property - Handbook of Targeted Cancer Therapy
Travel, Accommodations, Expenses - Bristol-Myers Squibb; EMD Serono; Millennium; Sarah Cannon Research Institute
 
Theodore Karrison
No Relationships to Disclose
 
Razelle Kurzrock
Leadership - CureMatch
Stock and Other Ownership Interests - Actuate Therapeutics; CureMatch
Honoraria - AACR; AACR; Actuate Therapeutics; Casdin Capital; Casdin Capital; Casdin Capital; Casdin Capital; Cedars-Sinai; Frankel Group; Global Biomarkers Consortium; Health Advances; Janssen; Jubilant Biosys; Kaiser Permanente; Mayo Clinic Cancer Center; NCCN; Northwestern University; NXT Health Strategies; NXT Health Strategies; Pancreatic Cancer Action Network; Segal Cancer Center; Seminars in Oncology; Sequenom; Sequenom; Sequenom; Sequenom; Sequenom; Sequenom; Sequenom; Sylvester Cancer Center; Sylvester Cancer Center; The Dedham Group; UCSD Genomics Program Talk; XBiotech; XBiotech; Yale Cancer Center
Consulting or Advisory Role - AACR; Actuate Therapeutics; CTRC-EAB San Antonio; Janssen; Jubilant Biosys; Merck; SAIC NCI CCCT IDSE; Sequenom; XBiotech
Research Funding - Centocor Ortho Biotech; EMD Serono; EMD Serono; EMD Serono; Exelixis; Foundation Medicine; Genentech Mypath; GlaxoSmithKline; GlaxoSmithKline; Guardant Health; Merck; Merck; Merck Serono; Novartis; Pfizer; Roche/Genentech; Sequenom; XBiotech
Patents, Royalties, Other Intellectual Property - Patent; Patent; Patent; Patent
Travel, Accommodations, Expenses - AACR; AACR; ASCPT; Association of American Cancer Institutes; Caris Centers of Excellence; Caris Centers of Excellence; Cedars-Sinai; CureMatch; EMD Serono; EMD Serono & Quintiles; EMD Serono & Quintiles; FDA-OCRA; Gateway Research Advisory Committee; Gateway Research Advisory Committee; Genentech; Global Biomarkers Consortium; Global Source Ventures/Novena Therapeutics; Guardant Health; Guardant Health; ICRP; Journal of Precision Medicine; Kaiser Permanente; Lynx Group; Mayo Clinic Cancer Center; MedImmune/JK Associates Medical Communications Group; Meyer; Orbimed/Global Source Ventures; Pancreatic Cancer Action Network; Sylvester Cancer Center; WIN Pharma; WIN Pharma; WIN Pharma; WIN Pharma; WIN Pharma; WIN Pharma; WIN Pharma; WIN Pharma
 
Linda A. Janisch
No Relationships to Disclose
 
Elizabeth Hoening
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
 
Shekman Wong
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
 
Wijith Munasinghe
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
 
Peter J Ansell
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
 
Mark J. Ratain
Stock and Other Ownership Interests - Biscayne Pharmaceuticals; PrescriptIQ; Venaxis
Consulting or Advisory Role - AbbVie; Amgen; Biomarin; Biscayne Pharmaceuticals; Circle Pharma; Cyclacel; Drais Pharmaceuticals; Genentech/Roche; Portola Pharmaceuticals; Shionogi; Venaxis
Research Funding - Dicerna (Inst); OncoTherapy Science (Inst)
Patents, Royalties, Other Intellectual Property - pending patent related to a genomic prescribing system; pending patent related to a genomic prescribing system (Inst); royalties related to UGT1A1 genotyping for irinotecan; royalties related to UGT1A1 genotyping for irinotecan (Inst)
Expert Testimony - multiple generic companies
 
Lawrence H. Schwartz
No Relationships to Disclose
 
David S. Hong
Stock and Other Ownership Interests - MolecularMatch; Oncorena
Honoraria - Adaptimmune; Baxter; Bayer; Merrimack
Consulting or Advisory Role - Baxter; Bayer
Research Funding - Amgen; AstraZeneca; Daiichi Sankyo; Eisai; Genentech; Lilly; Merck; Mirati Therapeutics; miRNA Therapeutics; Novartis; Pfizer
Travel, Accommodations, Expenses - Loxo; miRNA Therapeutics
Other Relationship - Oncorena