The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I study of DKN-01 (D), an anti-DKK1 monoclonal antibody, in combination with gemcitabine (G) and cisplatin (C) in patients (pts) for first-line therapy with advanced biliary tract cancer (BTC).
 
Jennifer Rachel Eads
Consulting or Advisory Role - Amgen; Clearview Healthcare Partners; Exelixis; Merrimack; Oxigene; Portola Pharmaceuticals; Saatchi Wellness
Research Funding - AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); EMD Serono (Inst); HealthCare Pharmaceuticals (Inst); Merck (Inst); Novartis; Verastem (Inst)
Travel, Accommodations, Expenses - AstraZeneca/MedImmune (I)
 
Stacey Stein
No Relationships to Disclose
 
Anthony B. El-Khoueiry
Honoraria - Bayer; Bristol-Myers Squibb; Merrimack; Novartis
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; CytomX Therapeutics
Speakers' Bureau - Merrimack
 
Gulam Abbas Manji
Consulting or Advisory Role - Ardelyx
Research Funding - Merck; Plexxikon; Plexxikon
Travel, Accommodations, Expenses - Celgene; Celgene; Roche/Genentech
 
Thomas Adam Abrams
Honoraria - Celgene; Genentech/Roche; Merrimack
Consulting or Advisory Role - Aduro Biotech; Bristol-Myers Squibb
Research Funding - Celgene; Lilly
Travel, Accommodations, Expenses - Lilly
 
Alok A. Khorana
Honoraria - Bayer; Boehringer Ingelheim; Genentech; Halozyme; Janssen; LEO Pharma; Pfizer; Sanofi
Consulting or Advisory Role - Bayer; Genentech; Halozyme; Janssen; LEO Pharma; Pfizer; Sanofi
Research Funding - Amgen (Inst)
Travel, Accommodations, Expenses - Halozyme; Janssen; Pfizer
 
Rebecca A. Miksad
Consulting or Advisory Role - 2nd.MD; Acceleron Pharma; Advanced Medical; Advanced Medical (I); Grand Rounds; Onyx; OptumInsight
Research Funding - Acceleron Pharma (Inst); ArQule (Inst); Bayer/Onyx (Inst); Daiichi Sankyo (Inst); Eisai; Genentech (Inst); Newlink Genetics (Inst)
 
Devalingam Mahalingam
Consulting or Advisory Role - Amgen; Baxalta; Bayer
Speakers' Bureau - Amgen; Bayer; Genentech
Travel, Accommodations, Expenses - Baxalta
 
Cynthia A. Sirard
Employment - Leap Therapeutics
Stock and Other Ownership Interests - Leap Therapeutics
Patents, Royalties, Other Intellectual Property - Leap Therapeutics
 
Andrew X. Zhu
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Eisai; Merck; Novartis; Sanofi
Research Funding - Bayer (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst)
 
Lipika Goyal
Honoraria - Ribon Therapeutics
Research Funding - Dicerna; Exelixis; Leap Therapeutics; Taiho Pharmaceutical