The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1 study to evaluate the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of the OX40 agonist MEDI0562 in combination with tremelimumab or durvalumab in adult aubjects with advanced solid tumors.
 
Brendan D. Curti
Honoraria - Prometheus
Speakers' Bureau - Bristol-Myers Squibb; Prometheus
Research Funding - Bristol-Myers Squibb (Inst); MedImmune (Inst); Prometheus (Inst); Viralytics (Inst)
Travel, Accommodations, Expenses - Agonox; Prometheus
 
Todd Michael Bauer
Employment - Sarah Cannon Research Institute; Tennessee Oncology
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Calithera Biosciences (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Immunogen (Inst); Incyte (Inst); Kolltan Pharmaceuticals (Inst); Leap Therapeutics (Inst); Lilly (Inst); MabVax (Inst); MedImmune (Inst); medpacto (Inst); Merck (Inst); Merrimack (Inst); Millennium (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Principa Biopharma (Inst); Stemline Therapeutics (Inst)
 
Neeltje Steeghs
Consulting or Advisory Role - Lilly
Research Funding - AB Science; AstraZeneca; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; MedImmune; Novartis; Pfizer; Roche
 
A. Craig Lockhart
No Relationships to Disclose
 
Francis J. Giles
Honoraria - Novartis
Consulting or Advisory Role - Novartis
Travel, Accommodations, Expenses - Foundation Medicine; MedImmune; Novartis
 
John D. Powderly
Employment - BioCytics; Carolina BioOncology Institute
Leadership - BioCytics; Carolina BioOncology Institute
Stock and Other Ownership Interests - BioCytics; Bluebird Bio; Carolina BioOncology Institute; Juno Therapeutics; Kite, a Gilead company; Lion Biotechnologies; ZIOPHARM Oncology
Consulting or Advisory Role - AstraZeneca/MedImmune; Bristol-Myers Squibb; Curis; Genentech/Roche; TopAlliance BioSciences Inc
Speakers' Bureau - Bristol-Myers Squibb; Dendreon; Genentech/Roche; Merck
Research Funding - Abbvie; AstraZeneca/MedImmune; Bristol-Myers Squibb; Corvus Pharmaceuticals; Curis; EMD Serono; Genentech/Roche; Incyte; Lilly/ImClone; Macrogenics; Seagen; Top Alliance BioScience
Patents, Royalties, Other Intellectual Property - BioCytics is developing intellectual property for cellular immunotherapy
 
Naiyer A. Rizvi
Stock and Other Ownership Interests - Gritstone Bio
Honoraria - Merck Sharp & Dohme
Consulting or Advisory Role - AstraZeneca/MedImmune; Bristol-Myers Squibb; Genentech/Roche; Lilly; Merck Sharp & Dohme; Novartis; Pfizer
 
Jonathan Wade Goldman
Consulting or Advisory Role - Amgen; AstraZeneca; Bristol-Myers Squibb; Clovis Oncology; Genentech/Roche; Lilly; Trovagene; Vortex Biosciences
Research Funding - Abbvie; Array BioPharma; Astellas Pharma; Astex Pharmaceuticals; AstraZeneca/MedImmune; Bristol-Myers Squibb; Celgene; Clovis Oncology; Corvus Pharmaceuticals; Genentech/Roche; Lilly; Threshold Pharmaceuticals
 
Samir Khleif
Leadership - Advaxis
Stock and Other Ownership Interests - Advaxis
Honoraria - Cancer Panels; Genentech; INOVA Health System; MedThink
Consulting or Advisory Role - AstraZeneca/MedImmune; Gilead Sciences; Nektar; PDS
Research Funding - Advaxis (Inst); Argos Therapeutics (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); CureTech (Inst); MedImmune (Inst); Medivation (Inst); Merck Serono (Inst); Millennium (Inst); Newlink Genetics (Inst); PDS Biotechnology (Inst); Sanofi (Inst)
Travel, Accommodations, Expenses - Newlink Genetics
 
Matthew Joseph Gribbin
Employment - MedImmune
 
Jennifer T. McDevitt
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca/MedImmune
 
Scott A Hammond
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
Patents, Royalties, Other Intellectual Property - MedImmune
 
Victoria L Chiou
Employment - AstraZeneca/MedImmune
Stock and Other Ownership Interests - AstraZeneca
Research Funding - AstraZeneca/MedImmune (Inst)
 
Aurelien Marabelle
Honoraria - Bristol-Myers Squibb; Genentech; Merck; Roche
Consulting or Advisory Role - Amgen; Genentech; Novartis; Roche
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Merck; Roche
Research Funding - Merus (Inst)
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb; Roche