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Paracrine wnt-β-catenin signaling inhibition as a strategy to enhance the efficacy of anti-PD-1 antibody (Ab) therapy in a transgenic model of melanoma. |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - OncoMed |
Patents, Royalties, Other Intellectual Property - OncoMed (Inst) |
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Honoraria - Genentech/Roche; Lilly/ImClone |
Consulting or Advisory Role - Acceleron Pharma; Bristol-Myers Squibb; Genentech/Roche; GlaxoSmithKline; Incyte; Lilly; Novartis; OncoMed; TRACON Pharma |
Research Funding - Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Macrogenics (Inst); NCI (Inst); Novartis (Inst); Regeneron (Inst); TRACON Pharma (Inst) |
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Consulting or Advisory Role - Amgen; Bayer; Boehringer Ingelheim; Celgene; Genentech/Roche; Onyx |
Research Funding - Abbvie (Inst); Bayer (Inst); Exelixis (Inst); Gilead Sciences (Inst); MedImmune (Inst); OncoMed (Inst); Regeneron (Inst); Roche/Genentech (Inst); Sanofi (Inst) |
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Stock and Other Ownership Interests - Bellicum Pharmaceuticals |
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Consulting or Advisory Role - EMD Serono |
Research Funding - Celldex; Incyte; medpacto; Merck; OncoMed |