The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A pediatric phase I study of larotrectinib, a highly selective inhibitor of the tropomyosin receptor kinase (TRK) family.
 
Theodore Willis Laetsch
Consulting or Advisory Role - Loxo; Novartis
Research Funding - Amgen; Lilly; Merck
Travel, Accommodations, Expenses - Celgene
 
Steven G. DuBois
Honoraria - Loxo
Consulting or Advisory Role - Loxo
Research Funding - Curis (Inst); Lilly (Inst); Merck (Inst); Millennium (Inst); Novartis (Inst); Roche/Genentech (Inst)
Travel, Accommodations, Expenses - Loxo
 
Ramamoorthy Nagasubramanian
No Relationships to Disclose
 
Brian Turpin
No Relationships to Disclose
 
Leo Mascarenhas
Honoraria - Bayer
Consulting or Advisory Role - Bayer; Lilly (Inst)
Research Funding - AstraZeneca/MedImmune (Inst)
Travel, Accommodations, Expenses - AstraZeneca/MedImmune; Bayer; Lilly
 
Noah Federman
No Relationships to Disclose
 
Mark Reynolds
Consulting or Advisory Role - Loxo
 
Steven Smith
Consulting or Advisory Role - Loxo
 
Scott Cruickshank
Consulting or Advisory Role - Loxo
 
Michael Craig Cox
Employment - Loxo
 
Alberto S. Pappo
No Relationships to Disclose
 
Douglas S. Hawkins
No Relationships to Disclose