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A phase 1/1b multicenter, open-label, dose escalation and dose expansion study to evaluate the safety, pharmacokinetics, immunogenicity, and antitumor activity of MEDI3726 in patients with metastatic, castration-resistant prostate cancer who have received prior treatment with abiraterone or enzalutamide. |
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Employment - Virginia Oncology Associates |
Speakers' Bureau - Genentech; Medivation/Astellas |
Travel, Accommodations, Expenses - Genentech; Medivation/Astellas |
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Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Janssen; MSD; Novartis; Pfizer; Roche; Sanofi |
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Stock and Other Ownership Interests - Bellicum Pharmaceuticals; TYME |
Honoraria - Astellas Pharma; Bayer; Bellicum Pharmaceuticals; Exelixis; Ferring; Genentech; Johnson & Johnson; Medivation; Merck Serono; Millennium; Pfizer; Progenics; Sanofi |
Consulting or Advisory Role - Bayer; Bellicum Pharmaceuticals; Dendreon; Exelixis; Ferring; Johnson & Johnson; Medivation; Millennium; Pfizer; Sanofi |
Research Funding - Astellas Medivation; Dendreon; Endocyte; Genentech; gtx; Johnson & Johnson; Merck; Millennium; Novartis; Oncogenex; progenics; Progenics; Sanofi |
Expert Testimony - Celgene; sanofi |
Travel, Accommodations, Expenses - Bayer; Bellicum Pharmaceuticals; Celgene; Dendreon; Exelixis; Ferring; Johnson & Johnson; Medivation; Millennium; Oncogenex; Pfizer; Progenics; Sanofi |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - BZL Biologics |
Consulting or Advisory Role - ADC Therapeutics; Avidity Nanomedicines; BZL Biologics; Tarveda Therapeutics |
Patents, Royalties, Other Intellectual Property - Cornell University |
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Employment - ADC Therapeutics |
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Employment - ADC Therapeutics |
Stock and Other Ownership Interests - ADC Therapeutics |
Honoraria - ADC Therapeutics |
Research Funding - ADC Therapeutics |
Patents, Royalties, Other Intellectual Property - ADC Therapeutics |
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Employment - AstraZeneca/MedImmune |
Stock and Other Ownership Interests - AstraZeneca/MedImmune |
Research Funding - AstraZeneca/MedImmune |
Patents, Royalties, Other Intellectual Property - AstraZeneca/MedImmune |
Travel, Accommodations, Expenses - AstraZeneca/MedImmune |
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Stock and Other Ownership Interests - AstraZeneca; MedImmune |
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Employment - AstraZeneca; AstraZeneca (I); Johnson & Johnson; Johnson & Johnson (I) |
Stock and Other Ownership Interests - AstraZeneca; Pfizer |
Travel, Accommodations, Expenses - AstraZeneca (I) |
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No Relationships to Disclose |
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Honoraria - AstraZeneca; Genentech; Genmab; GlaxoSmithKline; Merck; Pfizer; Sanofi |
Consulting or Advisory Role - AstraZeneca; Genentech; Genmab; GlaxoSmithKline; Merck; Pfizer; Sanofi |
Research Funding - AstraZeneca (Inst); Genentech (Inst); Genmab (Inst); GlaxoSmithKline (Inst); Merck (Inst); Sanofi (Inst) |