The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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CX-1158-101: A first-in-human phase 1 study of CB-1158, a small molecule inhibitor of arginase, as monotherapy and in combination with an anti-PD-1 checkpoint inhibitor in patients (pts) with solid tumors.
 
Kyriakos P. Papadopoulos
Research Funding - Abbvie (Inst); Amgen (Inst); ARMO BioSciences (Inst); ArQule (Inst); Calithera Biosciences (Inst); Curegenix (Inst); Daiichi Sankyo (Inst); GlaxoSmithKline (Inst); Incyte (Inst); MedImmune (Inst); Merck (Inst); Novartis (Inst); Onyx (Inst); Peloton Therapeutics (Inst); Regeneron (Inst); Sanofi (Inst)
 
Frank Yung-Chin Tsai
No Relationships to Disclose
 
Todd Michael Bauer
Employment - Sarah Cannon Research Institute; Tennessee Oncology
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Calithera Biosciences (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Immunogen (Inst); Incyte (Inst); Kolltan Pharmaceuticals (Inst); Leap Therapeutics (Inst); Lilly (Inst); MabVax (Inst); MedImmune (Inst); medpacto (Inst); Merck (Inst); Merrimack (Inst); Millennium (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Principa Biopharma (Inst); Stemline Therapeutics (Inst)
 
Lucas Muigai
Employment - Calithera Biosciences
Stock and Other Ownership Interests - Calithera Biosciences
Travel, Accommodations, Expenses - Calithera Biosciences
 
Yu Liang
Employment - Calithera Biosciences
Stock and Other Ownership Interests - Calithera Biosciences
Travel, Accommodations, Expenses - Calithera Biosciences
 
Mark K. Bennett
Employment - Calithera Biosciences
Stock and Other Ownership Interests - Calithera Biosciences
Patents, Royalties, Other Intellectual Property - Calithera Biosciences (Inst)
Travel, Accommodations, Expenses - Calithera Biosciences
 
Keith W. Orford
Employment - Calithera Biosciences
Leadership - Calithera Biosciences
Stock and Other Ownership Interests - Calithera Biosciences
Travel, Accommodations, Expenses - Calithera Biosciences
 
Siqing Fu
No Relationships to Disclose