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Integrated biomarker analysis for 412 renal cell cancer (RCC) patients (pts) treated on the phase 3 COMPARZ trial: Correlating common mutation events in PBRM1 and BAP1 with angiogenesis expression signatures and outcomes on tyrosine kinase inhibitor (TKI) therapy. |
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Consulting or Advisory Role - Alexion Pharmaceuticals; Calithera Biosciences; Exelixis; GlaxoSmithKline; Natera; Novartis; Pfizer |
Research Funding - Bristol-Myers Squibb; Genentech/Roche; Pfizer |
Travel, Accommodations, Expenses - Novartis; Takeda |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Novartis |
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Stock and Other Ownership Interests - Novartis |
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No Relationships to Disclose |
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Research Funding - Bristol-Myers Squibb |
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Leadership - Bristol-Myers Squibb; Cancer Genetics; Illumina |
Stock and Other Ownership Interests - Gritstone Bio |
Research Funding - Bristol-Myers Squibb |
Patents, Royalties, Other Intellectual Property - Neoantigen discovery and genomic biomarkers for immunotherapy response |
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Honoraria - NCCN; UpToDate |
Consulting or Advisory Role - alligent; AstraZeneca; Bayer; Bristol-Myers Squibb; Cerulean Pharma; Eisai; Exelixis; Foundation Medicine; GlaxoSmithKline; Merck; Novartis; Peloton Therapeutics; Pfizer; Prometheus; Roche/Genentech |
Research Funding - Agensys (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Celldex (Inst); Exelixis (Inst); GlaxoSmithKline (Inst); Merck (Inst); Novartis (Inst); Peloton Therapeutics (Inst); Pfizer (Inst); Roche/Genentech (Inst); TRACON Pharma (Inst) |
Travel, Accommodations, Expenses - advisory boards/consultancy |
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Honoraria - Chugai Pharma |
Consulting or Advisory Role - Chugai Pharma; Eisai; Novartis |
Research Funding - CGI; Eisai; Novartis; Pfizer |
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Consulting or Advisory Role - Eisai; Exelixis; Novartis; Pfizer |
Research Funding - Bristol-Myers Squibb (Inst); Eisai (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Pfizer (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb |
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No Relationships to Disclose |