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SWOG S1221: A phase 1 dose escalation study co-targeting MAPK-dependent and MAPK-independent BRAF inhibitor resistance in BRAF mutant advanced solid tumors with dabrafenib, trametinib, and GSK2141795 (ClinicalTrials.gov NCT01902173). |
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Research Funding - AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Merck (Inst); Novartis (Inst); Oncosec (Inst) |
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No Relationships to Disclose |
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Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Eisai; Genentech/Roche; Immunocore; Merck |
Speakers' Bureau - Genentech/Roche; Janssen Oncology |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Genentech/Roche; Janssen; Merck |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Castle Biosciences; Genentech; Novartis |
Research Funding - Amgen (Inst); Array BioPharma (Inst); Bristol-Myers Squibb (Inst); Castle Biosciences (Inst); Celldex (Inst); Checkmate Pharmaceuticals (Inst); Dynavax Technologies (Inst); Genentech (Inst); Incyte (Inst); Merck (Inst); Millennium (Inst); Novartis (Inst); Reata Pharmaceuticals (Inst); Syndax (Inst); Takeda (Inst) |
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Consulting or Advisory Role - Novartis |
Speakers' Bureau - Novartis |
Research Funding - Novartis (Inst) |
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Honoraria - Bristol-Myers Squibb |
Consulting or Advisory Role - Abbvie/Genentech; Bristol-Myers Squibb |
Speakers' Bureau - Abbvie/Genentech; Bristol-Myers Squibb |
Research Funding - Bristol-Myers Squibb (Inst); Macrogenics (Inst); MedImmune (Inst); Seagen (Inst) |
Travel, Accommodations, Expenses - Abbvie/Genentech; Bristol-Myers Squibb |
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Speakers' Bureau - Bristol-Myers Squibb; Prometheus |
Research Funding - Bristol-Myers Squibb (Inst); MedImmune (Inst); Prometheus (Inst); Viralytics (Inst) |
Travel, Accommodations, Expenses - Agonox; Prometheus |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Arcus Ventures; Compugen; CytomX Therapeutics; Five Prime Therapeutics; FLX Bio; Kite, a Gilead company |
Consulting or Advisory Role - Amgen; Genentech/Roche; Merck; Novartis |