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A phase I study to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activities of daily oral BAL101553, a novel tumor checkpoint controller (TCC) in adult patients with progressive or recurrent glioblastoma (GBM) or high-grade glioma. |
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Alvaro Henrique Ingles Garces |
No Relationships to Disclose |
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Honoraria - Bristol-Myers Squibb; Roche/Genentech |
Consulting or Advisory Role - Astex Pharmaceuticals; AstraZeneca; Bayer; Clovis Oncology; Karus Therapeutics; Mission Therapeutics; MSD Oncology; Novartis; Pierre Fabre; Roche/Genentech; Vertex |
Speakers' Bureau - Novartis |
Research Funding - AstraZeneca/MedImmune (Inst); Clovis Oncology (Inst); Eisai (Inst); Etherapeutics (Inst); Ipsen (Inst); vertex (Inst) |
Patents, Royalties, Other Intellectual Property - Named on patent of use of PARP inhibitor rucaparib (Inst) |
Travel, Accommodations, Expenses - MSD Oncology |
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No Relationships to Disclose |
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Rebecca Sophie Kristeleit |
Honoraria - AstraZeneca; Clovis Oncology; Roche/Genentech |
Consulting or Advisory Role - Cerulean Pharma; Clovis Oncology; Lytix Biopharma; Medivation; Roche/Genentech; Sotio |
Travel, Accommodations, Expenses - Basilea; Clovis Oncology; Valirx |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Leadership - NeoGenomics Laboratories |
Stock and Other Ownership Interests - NeoGenomics Laboratories |
Consulting or Advisory Role - Basilea; Jazz Pharmaceuticals; Medivation; Nektar |
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Employment - Novartis (I) |
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Consulting or Advisory Role - Basilea; SCED Bioscience Institute |
Research Funding - Basilea |
Patents, Royalties, Other Intellectual Property - Harvard Medical School; Novartis |
Expert Testimony - SCED Bioscience Institute; Swiss Re |
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Stock and Other Ownership Interests - Basilea |
Research Funding - Basilea |
Patents, Royalties, Other Intellectual Property - Basilea (Inst) |
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Stock and Other Ownership Interests - Basilea |
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Marc Frederick Engelhardt |
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Stock and Other Ownership Interests - Basilea |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Honoraria - Bristol-Myers Squibb |
Consulting or Advisory Role - Baxter (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Eisai (Inst); Karus Therapeutics (Inst) |
Speakers' Bureau - Bristol-Myers Squibb; Celgene |
Research Funding - AstraZeneca (Inst); Basilea (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Eisai (Inst); GlaxoSmithKline (Inst); Immunocare Therapies (Inst); Lilly (Inst); Merck (Inst); Roche (Inst); Verastem (Inst); Vertex (Inst) |
Travel, Accommodations, Expenses - Bristol-Myers Squibb |
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Travel, Accommodations, Expenses - BMS Brazil |