The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Consulting or Advisory Role - AstraZeneca; BMS Brazil; Boehringer Ingelheim; Clovis Oncology
Speakers' Bureau - Novartis; Pfizer
Travel, Accommodations, Expenses - BMS Brazil; Novartis

A phase I study to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activities of daily oral BAL101553, a novel tumor checkpoint controller (TCC) in adult patients with progressive or recurrent glioblastoma (GBM) or high-grade glioma.
 
Alvaro Henrique Ingles Garces
No Relationships to Disclose
 
Elizabeth R. Plummer
Honoraria - Bristol-Myers Squibb; Roche/Genentech
Consulting or Advisory Role - Astex Pharmaceuticals; AstraZeneca; Bayer; Clovis Oncology; Karus Therapeutics; Mission Therapeutics; MSD Oncology; Novartis; Pierre Fabre; Roche/Genentech; Vertex
Speakers' Bureau - Novartis
Research Funding - AstraZeneca/MedImmune (Inst); Clovis Oncology (Inst); Eisai (Inst); Etherapeutics (Inst); Ipsen (Inst); vertex (Inst)
Patents, Royalties, Other Intellectual Property - Named on patent of use of PARP inhibitor rucaparib (Inst)
Travel, Accommodations, Expenses - MSD Oncology
 
Juanita Suzanne Lopez
No Relationships to Disclose
 
Rebecca Sophie Kristeleit
Honoraria - AstraZeneca; Clovis Oncology; Roche/Genentech
Consulting or Advisory Role - Cerulean Pharma; Clovis Oncology; Lytix Biopharma; Medivation; Roche/Genentech; Sotio
Travel, Accommodations, Expenses - Basilea; Clovis Oncology; Valirx
 
Julie MacDonald
No Relationships to Disclose
 
Lorna Sweeting
No Relationships to Disclose
 
Michael-John Devlin
No Relationships to Disclose
 
Yvette Drew
No Relationships to Disclose
 
Alison L. Hannah
Leadership - NeoGenomics Laboratories
Stock and Other Ownership Interests - NeoGenomics Laboratories
Consulting or Advisory Role - Basilea; Jazz Pharmaceuticals; Medivation; Nektar
 
Nicola Aceto
Employment - Novartis (I)
Honoraria - Swiss Re
Consulting or Advisory Role - Basilea; SCED Bioscience Institute
Research Funding - Basilea
Patents, Royalties, Other Intellectual Property - Harvard Medical School; Novartis
Expert Testimony - SCED Bioscience Institute; Swiss Re
 
Stephanie Anderson
Employment - Basilea
 
Heidi A Lane
Employment - Basilea
Stock and Other Ownership Interests - Basilea
Research Funding - Basilea
Patents, Royalties, Other Intellectual Property - Basilea (Inst)
 
Patrice Larger
Employment - Basilea
 
Martina Maurer
Employment - Basilea
 
Phil McKernan
Employment - Basilea
Stock and Other Ownership Interests - Basilea
 
Marc Frederick Engelhardt
Employment - Basilea
Stock and Other Ownership Interests - Basilea
 
Alastair Greystoke
No Relationships to Disclose
 
Niamh Coleman
No Relationships to Disclose
 
T.R. Jeffry Evans
Honoraria - Bristol-Myers Squibb
Consulting or Advisory Role - Baxter (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Eisai (Inst); Karus Therapeutics (Inst)
Speakers' Bureau - Bristol-Myers Squibb; Celgene
Research Funding - AstraZeneca (Inst); Basilea (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Eisai (Inst); GlaxoSmithKline (Inst); Immunocare Therapies (Inst); Lilly (Inst); Merck (Inst); Roche (Inst); Verastem (Inst); Vertex (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb
 
Paul James Mulholland
Travel, Accommodations, Expenses - BMS Brazil