The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Results from the biomarker-driven basket trial of RO5126766 (CH5127566), a potent RAF/MEK inhibitor, in RAS- or RAF-mutated malignancies including multiple myeloma.
 
Maxime Chenard-Poirier
No Relationships to Disclose
 
Martin Kaiser
Honoraria - Amgen; Celgene; Janssen Biotech
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Celgene; Chugai Pharma; Janssen; Takeda
Research Funding - Celgene
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Takeda
 
Kevin Boyd
Honoraria - Celgene; Janssen; Novartis
Consulting or Advisory Role - Celgene; Novartis
Travel, Accommodations, Expenses - Janssen
 
Priya Sriskandarajah
No Relationships to Disclose
 
Anastasia Constantinidou
No Relationships to Disclose
 
Samuel John Harris
Travel, Accommodations, Expenses - Bristol-Myers Squibb
 
Sonia Serrano Fandos
No Relationships to Disclose
 
Alison Ryan
No Relationships to Disclose
 
Karolina Witt
No Relationships to Disclose
 
Joanna C Dawes
No Relationships to Disclose
 
Mona Parmar
No Relationships to Disclose
 
Alison Joanne Turner
No Relationships to Disclose
 
Holly Tovey
Research Funding - AstraZeneca (Inst); Johnson & Johnson (Inst); Pfizer (Inst)
Patents, Royalties, Other Intellectual Property - Employees of the ICR are subject to a "Rewards to Inventors Scheme" which may reward contributors to a programme that is subsequently licensed.
 
Emma Hall
Research Funding - Accuray (Inst); AstraZeneca (Inst); Bayer (Inst); Cambridge Major Laboratories (Inst); Kyowa Hakko Kirin (Inst); Sanofi (Inst)
 
Raquel Perez Lopez
No Relationships to Disclose
 
Nina Tunariu
Speakers' Bureau - Janssen; Sanofi
 
Juanita Suzanne Lopez
No Relationships to Disclose
 
Johann S. De Bono
Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi
Research Funding - AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); PARP inhibitors and DNA repair defects (Inst)
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex
 
Udai Banerji
Employment - Institute of Cancer Research
Consulting or Advisory Role - Astex Pharmaceuticals; Novartis
Research Funding - AstraZeneca (Inst); Chugai Pharma (Inst); Onyx (Inst)