The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors.
 
Monica M. Mita
No Relationships to Disclose
 
Patricia LoRusso
Leadership - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech/Roche; Novartis
Honoraria - Genentech/Roche
Consulting or Advisory Role - Alexion Pharmaceuticals; Astellas Pharma; Astex Pharmaceuticals; Boehringer Ingelheim; Genentech; Novartis; Pfizer
Speakers' Bureau - Genentech
Research Funding - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech (Inst); Immunogen (Inst); Merrimack (Inst); Novartis (Inst); Pfizer; Taiho Pharmaceutical (Inst); Tensha Therapeutics (Inst)
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Genentech/Roche
 
Grant A. McArthur
Employment - Yale Cancer Center
Honoraria - Alexion Pharmaceuticals; ARIAD; Genentech; Genmab; Glenmark; Menarini; Novartis; Pfizer
Research Funding - Yale Cancer Center (Inst)
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Ariad; Genentech; Genmab; Glenmark; Menarini; Novartis; Pfizer
Other Relationship - Five Prime Therapeutics; Halozyme
 
Edward S. Kim
Honoraria - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
 
Gordon L. Bray
Employment - Celgene
Stock and Other Ownership Interests - Celgene
Research Funding - Celgene (Inst)
Patents, Royalties, Other Intellectual Property - Celgene
Travel, Accommodations, Expenses - Celgene
 
Nanette H Hock
Employment - Celgene; Gilead Sciences
Stock and Other Ownership Interests - Abbott Diagnostics; Boston Scientific
Travel, Accommodations, Expenses - Celgene; Gilead Sciences
 
Eric J. Laille
Employment - Celgene
Stock and Other Ownership Interests - Celgene
 
Ida Aronchik
Employment - Celgene
Stock and Other Ownership Interests - Celgene
Research Funding - Celgene
Patents, Royalties, Other Intellectual Property - Celgene
Travel, Accommodations, Expenses - Celgene
 
Ellen Filvaroff
Employment - Celgene
Stock and Other Ownership Interests - Celgene
Research Funding - Celgene
Patents, Royalties, Other Intellectual Property - Celgene
Travel, Accommodations, Expenses - Celgene
 
Xiaoling Wu
Employment - Celgene
Stock and Other Ownership Interests - Celgene
 
Johanna C. Bendell
Research Funding - Abbott/AbbVie (Inst); Agios (Inst); Apexigen (Inst); ARMO BioSciences (Inst); Array BioPharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Celldex (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); Five Prime Therapeutics (Inst); Forty Seven (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Kolltan Pharmaceuticals (Inst); Leap Therapeutics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Novartis (Inst); Oncogenex (Inst); OncoMed (Inst); Onyx (Inst); Sanofi (Inst); Stem CentRx (Inst); SynDevRx (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); TG Therapeutics (Inst)