The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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TAX-TORC: A phase I trial of vistusertib (AZD2014) in combination with weekly paclitaxel with integrated pharmacodynamic (PD) and molecular characterization (MC) studies.
 
Raghav Sundar
No Relationships to Disclose
 
Bristi Basu
Consulting or Advisory Role - Astex Pharmaceuticals (Inst); Baxter; Celgene (Inst)
Research Funding - Celgene
Travel, Accommodations, Expenses - Bayer; Bayer Health
 
Richard H. Wilson
Consulting or Advisory Role - Amgen; Clovis Oncology; Halozyme; Merck Serono; Servier; Sirtex Medical
Research Funding - Almac Group (Inst)
Travel, Accommodations, Expenses - Amgen; Merck Serono
 
James F. Spicer
No Relationships to Disclose
 
Robert Hugh Jones
No Relationships to Disclose
 
Matthew Krebs
Consulting or Advisory Role - Roche
 
Michael Brada
No Relationships to Disclose
 
Denis Charles Talbot
Honoraria - Pfizer; Pierre Fabre
Consulting or Advisory Role - Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Lilly; Novartis; Pfizer; Roche
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Ipsen; Lilly; Merck Sharp & Dohme; Novartis
 
Nicola Steele
Honoraria - Novartis; Pfizer
Consulting or Advisory Role - Boehringer Ingelheim; Bristol-Myers Squibb; Merck Sharp & Dohme
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Merck Serono (Inst); Novartis (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Boehringer Ingelheim; MSD Oncology; Pfizer
 
Emma Hall
Research Funding - Accuray; AstraZeneca; Bayer; Cambridge Major Laboratories; Kyowa Hakko Kirin; Sanofi
 
Holly Tovey
Research Funding - AstraZeneca (Inst); Johnson & Johnson (Inst); Pfizer (Inst)
Patents, Royalties, Other Intellectual Property - Employees of the ICR are subject to a "Rewards to Inventors Scheme" which may reward contributors to a programme that is subsequently licensed.
 
Suzanne Carreira
No Relationships to Disclose
 
Flavia M de Oliveira
Travel, Accommodations, Expenses - Labosphera
 
Karen E Swales
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); GlaxoSmithKline (Inst); Verastem (Inst); Vertex (Inst)
Patents, Royalties, Other Intellectual Property - Employees of The Institute of Cancer Research are subject to a Rewards to Inventors Scheme which may reward contributors to a programme that is subsequently licensed.
 
Geetha Balarajah
No Relationships to Disclose
 
Joanna C Dawes
No Relationships to Disclose
 
Mona Parmar
No Relationships to Disclose
 
Johann S. De Bono
Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi
Research Funding - AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); PARP inhibitors and DNA repair defects (Inst)
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex
 
Udai Banerji
Employment - Institute of Cancer Research
Consulting or Advisory Role - Astex Pharmaceuticals; Novartis
Research Funding - AstraZeneca (Inst); Chugai Pharma (Inst); Onyx (Inst)