The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I/II dose escalation and expansion study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK525762 in combination with fulvestrant in subjects with ER+ breast cancer.
 
Joseph A. Sparano
Stock and Other Ownership Interests - Metastat
Consulting or Advisory Role - AstraZeneca; Celgene; Celldex; Genentech/Roche; Juno Therapeutics; Lilly; Merrimack; Novartis; Pfizer; Prescient Therapeutics
Research Funding - Deciphera (Inst); Genentech/Roche (Inst); Merck (Inst); Merrimack (Inst); Novartis (Inst); Novartis (Inst); Prescient Therapeutics (Inst)
 
David W. Cescon
No Relationships to Disclose
 
Mafalda Oliveira
Consulting or Advisory Role - Puma Biotechnology; Roche/Genentech
Research Funding - AstraZeneca (Inst); Genentech/Roche (Inst)
 
Daniel G. Stover
No Relationships to Disclose
 
Elizabeth Tan-Chiu
Honoraria - Novartis
 
Brandon Edward Kremer
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Olena Barbash
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Yuehui Wu
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Lijoy Mathew
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - Clovis Oncology; Clovis Oncology (I); Exelixis; Exelixis (I); GlaxoSmithKline; GlaxoSmithKline (I); Novavax; Novavax (I)
 
Elizabeth Ann Cunningham
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Christopher L. Carpenter
Employment - GlaxoSmithKline (I)
Stock and Other Ownership Interests - GlaxoSmithKline
 
Marc S. Ballas
Employment - AstraZeneca; GlaxoSmithKline
Stock and Other Ownership Interests - Bristol-Myers Squibb; GlaxoSmithKline
Research Funding - AstraZeneca; GlaxoSmithKline
 
Arindam Dhar
Employment - GlaxoSmithKline
Leadership - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
Travel, Accommodations, Expenses - GlaxoSmithKline