The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
 
 
Honoraria - Amgen; AstraZeneca; Celgene; Eisai; GlaxoSmithKline; Janssen-Cilag; Novartis; Pfizer; Pierre Fabre; Roche; Teva
Consulting or Advisory Role - Amgen; Eisai; Genomic Health; Pierre Fabre; Roche

A randomized, double-blinded, controlled study of tucatinib (ONT-380) vs. placebo in combination with capecitabine (C) and trastuzumab (Tz) in patients with pretreated HER2+ unresectable locally advanced or metastatic breast carcinoma (mBC) (HER2CLIMB).
 
Carey K. Anders
Consulting or Advisory Role - Angiochem; Genentech/Roche; GERON; Kadmon; Lilly; Merrimack; Nektar; Novartis; Sanofi; to-BBB technologies BV
Research Funding - Angiochem (Inst); Cascadian Therapeutics (Inst); Geron (Inst); Lilly (Inst); Merck (Inst); Merrimack (Inst); Nektar (Inst); Novartis (Inst); Oncothyreon (Inst); Puma Biotechnology (Inst); Sanofi (Inst); Tesaro (Inst); to-BBB technologies BV (Inst)
Patents, Royalties, Other Intellectual Property - Jones and Bartlell; Up to Date.com
 
Rashmi Krishna Murthy
Consulting or Advisory Role - Daiichi Sankyo; Genentech
Research Funding - Merrimack (Inst); Oncothyreon (Inst)
Travel, Accommodations, Expenses - Genentech/Roche; Oncothyreon
 
Erika Paige Hamilton
Consulting or Advisory Role - Cascadian Therapeutics (Inst); Flatiron Health; Genentech/Roche (Inst); Pfizer (Inst)
Research Funding - AstraZeneca (Inst); BerGenBio (Inst); Cascadian Therapeutics (Inst); Curis (Inst); Genentech/Roche (Inst); Hutchison MediPharma (Inst); Kadmon (Inst); Lilly (Inst); Lycera (Inst); MedImmune (Inst); Medivation (Inst); Mersana (Inst); Millennium (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst); Rgenix (Inst); Stem CentRx (Inst); Syndax (Inst); TapImmune Inc. (Inst); Tesaro (Inst); Verastem (Inst); Zymeworks (Inst)
 
Virginia F. Borges
Research Funding - Abbott/AbbVie (Inst); Advaxis (Inst); Galena Biopharma (Inst); Incyte (Inst); Merrimack (Inst); Oncothyreon (Inst)
 
David A. Cameron
Research Funding - Novartis (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Novartis
 
Lisa A. Carey
Research Funding - Genentech/Roche (Inst); GlaxoSmithKline (Inst)
 
Volkmar Müller
No Relationships to Disclose
 
Giuseppe Curigliano
Consulting or Advisory Role - Pfizer; Roche/Genentech
Speakers' Bureau - Novartis; Roche/Genentech
Travel, Accommodations, Expenses - Roche/Genentech
 
Karen A. Gelmon
Consulting or Advisory Role - AstraZeneca; Merck; NanoString Technologies; Novartis; Pfizer
 
Gabriel N. Hortobagyi
Consulting or Advisory Role - Agendia; Bayer; Celgene; Lilly; Merck; Metastat; Novartis; Peregrine Pharmaceuticals; Roche
Research Funding - Novartis (Inst)
Travel, Accommodations, Expenses - Novartis
 
Ian E. Krop
Employment - AMAG Pharmaceuticals (I)
Leadership - AMAG Pharmaceuticals (I)
Stock and Other Ownership Interests - AMAG Pharmaceuticals (I)
Research Funding - Genentech
 
Sibylle Loibl
No Relationships to Disclose
 
Xavier B. Pivot
No Relationships to Disclose
 
Mark D. Pegram
Employment - Dava Oncology (I)
Consulting or Advisory Role - AstraZeneca; Genentech; Novartis; Pfizer
Expert Testimony - Novartis
Travel, Accommodations, Expenses - Genentech; Novartis; Pfizer
Other Relationship - AstraZeneca; Genentech; Novartis; Pfizer
 
Dennis J. Slamon
No Relationships to Disclose
 
Sara A. Hurvitz
Research Funding - Amgen (Inst); Bayer (Inst); Biomarin (Inst); Boehringer Ingelheim (Inst); Cascadian Therapeutics (Inst); Dignitana (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Lilly (Inst); Medivation (Inst); Merrimack (Inst); Novartis (Inst); OBI Pharma (Inst); Pfizer (Inst); Puma Biotechnology (Inst); sanofi (Inst)
Travel, Accommodations, Expenses - Bayer; Lilly; Novartis; OBI Pharma
 
Michaela L. Tsai
No Relationships to Disclose
 
Eric P. Winer
Consulting or Advisory Role - Genentech/Roche; Leap Therapeutics; Novartis; Verastem
Research Funding - Genentech/Roche (Inst); Novartis (Inst)
Travel, Accommodations, Expenses - Genentech/Roche