The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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MET amplification (amp) as a resistance mechanism to osimertinib.
 
Zofia Piotrowska
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Clovis Oncology
Research Funding - Guardant Health
 
Kenneth Stephen Thress
Employment - AstraZeneca
Stock and Other Ownership Interests - AstraZeneca
 
Meghan Mooradian
No Relationships to Disclose
 
Rebecca Suk Heist
Consulting or Advisory Role - ARIAD; Boehringer Ingelheim
Research Funding - Abbvie (Inst); Celgene (Inst); Debiopharm Group (Inst); Incyte (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Peregrine Pharmaceuticals (Inst); Roche (Inst); Takeda (Inst)
 
Christopher G. Azzoli
No Relationships to Disclose
 
Jennifer S. Temel
Research Funding - Pfizer (Inst)
 
Coleen Rizzo
No Relationships to Disclose
 
Rebecca J Nagy
Employment - Guardant Health
Stock and Other Ownership Interests - Guardant Health
 
Richard B. Lanman
Employment - Guardant Health; Veracyte
Leadership - Guardant Health
Stock and Other Ownership Interests - Guardant Health; Veracyte
Research Funding - Guardant Health
 
Scott N. Gettinger
No Relationships to Disclose
 
Tracey L. Evans
Honoraria - Celgene; Genentech; Genentech (I)
Consulting or Advisory Role - Celgene; Genentech; Genentech (I)
Speakers' Bureau - Genentech (I)
Travel, Accommodations, Expenses - Celgene; Genentech; Genentech (I)
 
Aaron N. Hata
Research Funding - Amgen (Inst); Novartis (Inst)
 
Alice Tsang Shaw
Honoraria - Foundation medicine; Novartis; Pfizer; Roche/Genentech
Consulting or Advisory Role - ARIAD; Blueprint Medicines; Daiichi Sankyo; EMD Serono; Genentech; Ignyta; KSQ Therapeutics; Novartis; Pfizer; Roche; Taiho Pharmaceutical
Research Funding - Novartis; Pfizer; Roche/Genentech
 
Lecia V. Sequist
Honoraria - AstraZeneca
Consulting or Advisory Role - ARIAD; AstraZeneca; Bristol-Myers Squibb; Genentech/Roche
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Clovis Oncology (Inst); Genentech (Inst); Johnson & Johnson (Inst); Merck (Inst); Merrimack (Inst); Novartis (Inst); Pfizer (Inst); Taiho Pharmaceutical (Inst)