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A phase 1 dose escalation study of eFT508, an inhibitor of mitogen-activated protein kinase-interacting serine/threonine kinase-1 (MNK-1) and MNK-2 in patients with advanced solid tumors. |
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Employment - HealthONE; Sarah Cannon Research Institute |
Research Funding - 3-V Biosciences; Abbvie; Aileron Therapeutics; ARMO BioSciences; AstraZeneca; Biothera; Celgene; Curegenix; Curis; DelMar Pharmaceuticals; eFFECTOR Therapeutics; EMD Serono; Fujifilm; Genmab; GlaxoSmithKline; Hutchison MediPharma; Incyte; Jounce Therapeutics; Kolltan Pharmaceuticals; Lilly; MedImmune; Millennium; Novartis; OncoMed; Precision Oncology; Regeneron; Strategia Therapeutics; Syndax; Taiho Pharmaceutical; Tesaro; Vegenics |
Patents, Royalties, Other Intellectual Property - Handbook of Targeted Cancer Therapy |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; EMD Serono; Millennium; Sarah Cannon Research Institute |
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Research Funding - Aileron Therapeutics (Inst); ARMO BioSciences (Inst); AstraZeneca (Inst); BioMed Valley Discoveries (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Calithera Biosciences (Inst); Celldex (Inst); Celldex (Inst); eFFECTOR Therapeutics (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Immunocore (Inst); Janssen Oncology (Inst); MedImmune (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Phosplatin Therapeutics (Inst); Roche (Inst); Roche (Inst); Tesaro (Inst) |
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Honoraria - Genentech; Roche |
Consulting or Advisory Role - Celgene; Clearlight Diagnostics; Genentech; Inflection Biosciences; Novartis; Pieris Pharmaceuticals; Roche |
Research Funding - Aileron Therapeutics; AstraZeneca; Bayer; Calithera Biosciences; Curis; CytomX Therapeutics; Debiopharm Group; Effective Pharmaceuticals; Genentech; Jounce Therapeutics; Novartis; PUMA Biotechnology; Taiho Pharmaceutical; Verastem; Zymeworks |
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Employment - Cleveland BioLabs; Sound Clinical Solutions, SP |
Leadership - Cleveland BioLabs; Sound Clinical Solutions, SP |
Stock and Other Ownership Interests - eFFECTOR Therapeutics |
Consulting or Advisory Role - eFFECTOR Therapeutics |
Expert Testimony - SRS Acquiom |
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Stock and Other Ownership Interests - Amgen; Gilead Sciences; Pfizer |
Consulting or Advisory Role - Auspex Pharmaceuticals; eFFECTOR Therapeutics; Mapp Biopharmaceutical; Teva |
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Employment - eFFECTOR Therapeutics |
Leadership - eFFECTOR Therapeutics |
Stock and Other Ownership Interests - eFFECTOR Therapeutics |
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Employment - eFFECTOR Therapeutics |
Stock and Other Ownership Interests - eFFECTOR Therapeutics; IncellDx |
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Employment - eFFECTOR Therapeutics |
Stock and Other Ownership Interests - eFFECTOR Therapeutics |
Research Funding - eFFECTOR Therapeutics |
Patents, Royalties, Other Intellectual Property - eFFECTOR Therapeutics |
Travel, Accommodations, Expenses - eFFECTOR Therapeutics |
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Employment - Abbvie; eFFECTOR Therapeutics |
Stock and Other Ownership Interests - Abbvie |
Research Funding - Abbvie; eFFECTOR Therapeutics |
Patents, Royalties, Other Intellectual Property - AbbVie (Inst) |
Travel, Accommodations, Expenses - Abbvie; eFFECTOR Therapeutics |
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No Relationships to Disclose |
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Employment - eFFECTOR Therapeutics; Pfizer |
Leadership - eFFECTOR Therapeutics |
Stock and Other Ownership Interests - eFFECTOR Therapeutics; Pfizer |
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Honoraria - Bristol-Myers Squibb; Exelis; Genentech; Gilead Sciences; Medivation |
Consulting or Advisory Role - Guardant Health |
Speakers' Bureau - Bristol-Myers Squibb; Exelis; Genentech; Gilead Sciences; Medivation |