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YES1 amplification as a mechanism of acquired resistance (AR) to EGFR tyrosine kinase inhibitors (TKIs) identified by a transposon mutagenesis screen and clinical genomic testing. |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Employment - Girihlet Inc. |
Leadership - Girihlet Inc. |
Stock and Other Ownership Interests - Girihlet Inc. |
Patents, Royalties, Other Intellectual Property - Girihlet Inc.; Icahn School of Medicine |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Consulting or Advisory Role - Roche |
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Patents, Royalties, Other Intellectual Property - Ludwig Institute for Cancer Research |
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Patents, Royalties, Other Intellectual Property - Memorial Sloan-Kettering Cancer Center |
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Honoraria - NCCN; Novartis; Pfizer; Qiagen; Sequenom |
Consulting or Advisory Role - Ariad; ARIAD; Clovis Oncology; Genoptix; Novartis; Novartis |
Research Funding - AstraZeneca; Novartis |
Travel, Accommodations, Expenses - Pfizer |
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Consulting or Advisory Role - ARIAD; AstraZeneca; Genentech/Roche |
Research Funding - Genentech/Roche (Inst); Puma Biotechnology (Inst) |
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Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Lilly |
Research Funding - Astellas Pharma; AstraZeneca; Clovis Oncology; Incyte; Lilly |
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Consulting or Advisory Role - Genentech; Novartis; Novartis; Roche |
Research Funding - ARIAD (Inst); GlaxoSmithKline (Inst); Infinity Pharmaceuticals (Inst); Millennium (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst) |
Travel, Accommodations, Expenses - Novartis |
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No Relationships to Disclose |
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Consulting or Advisory Role - Novartis |
Research Funding - AstraZeneca; Kolltan Pharmaceuticals; Roche |
Patents, Royalties, Other Intellectual Property - I am a co-inventor on a patent licensed by MSKCC to Molecular MD for T790M testing |
Travel, Accommodations, Expenses - Novartis |
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Consulting or Advisory Role - NCCN/AstraZeneca; NCCN/Boehringer Ingelheim |
Research Funding - Loxo (Inst) |