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Phase 1-2 study of progesterone receptor (PR) inhibition with extended-release (ER) onapristone (ONA) alone or in combination with abiraterone (AA) in patients (pts) with castration-resistant prostate cancer (CRPC) incorporating plasma DNA analysis to define androgen receptor (AR) status. |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Travel, Accommodations, Expenses - AstraZeneca; Sanofi |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Employment - Arno Therapeutics |
Leadership - Arno Therapeutics |
Stock and Other Ownership Interests - Arno Therapeutics |
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Consulting or Advisory Role - Arno Therapeutics |
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Employment - Arno Therapeutics |
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Employment - Arno Therapeutics |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Honoraria - Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Ipsen; Janssen; MSD Oncology; Novartis; Pfizer; Roche/Genentech; Sanofi; Seagen |
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Exelixis (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Astellas Pharma; Bayer; Ipsen; Janssen; MSD |
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Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi |
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi |
Research Funding - AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst) |
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); PARP inhibitors and DNA repair defects (Inst) |
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex |
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Honoraria - Astellas Pharma; Janssen |
Consulting or Advisory Role - Abbott Laboratories; Astellas Pharma; Bayer; ESSA; Janssen-Cilag; Medivation; Millennium; Novartis; Ventana Medical Systems; Veridex |
Speakers' Bureau - Astellas Pharma; Janssen; Sanofi; Takeda; Ventana Medical Systems |
Research Funding - Arno Therapeutics (Inst); AstraZeneca (Inst); Janssen (Inst) |
Patents, Royalties, Other Intellectual Property - I am on The ICR rewards to inventors list of abiraterone acetate. |
Travel, Accommodations, Expenses - Abbott Laboratories; Astellas Pharma; Astellas Pharma (I); Bayer; ESSA; Janssen; Janssen (I); Medivation; Ventana Medical Systems |
Other Relationship - Institute of Cancer Research |