The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Analysis of DNA damage response (DDR) genes and tumor mutational burden (TMB) across 17,486 carcinomas of the tubular GI tract: Implications for therapy.
 
Aparna Raj Parikh
Employment - Genentech
 
Yuting He
Employment - Foundation Medicine
 
Theodore S. Hong
Research Funding - Novartis (Inst); Taiho Pharmaceutical
 
Ryan Bruce Corcoran
Consulting or Advisory Role - Amgen; Astex Pharmaceuticals; Avidity Nanomedicines; Bristol-Myers Squibb; Genentech; Merrimack; N-of-One; Roche; Shire; Taiho Pharmaceutical
Research Funding - AstraZeneca; Sanofi
 
Jeffrey W. Clark
No Relationships to Disclose
 
David P. Ryan
Stock and Other Ownership Interests - MPM Capital
Honoraria - Research to Practice; UpToDate
Consulting or Advisory Role - MPM Capital
Patents, Royalties, Other Intellectual Property - Johns Hopkins University Press; McGraw Hill Chapter Royalties
 
Daniel V.T. Catenacci
Honoraria - Amgen; Bristol-Myers Squibb; Five Prime Therapeutics; Foundation Medicine; Genentech/Roche; Genmab; Gritstone Bio; Guardant Health; Lilly; Merck; NantWorks; OncoPlex Diagnostics; Taiho Pharmaceutical
Consulting or Advisory Role - Amgen; Genentech/Roche; OncoPlex Diagnostics
Speakers' Bureau - Foundation Medicine; Genentech/Roche; Guardant Health; Lilly; NantWorks
Research Funding - Genentech; OncoPlex Diagnostics
 
Joseph Chao
Consulting or Advisory Role - Bayer; Boston Biomedical; Five Prime Therapeutics; Lilly
Research Funding - Merck (Inst); Novonco Therapeutics (Inst)
 
Marwan Fakih
Honoraria - Sirtex Medical
Consulting or Advisory Role - Amgen; Array BioPharma; Genentech/Roche; Merck; Sirtex Medical
Speakers' Bureau - Amgen; Sirtex Medical; Taiho Pharmaceutical
Research Funding - Merck (Inst); Novartis (Inst)
 
Jeffrey S. Ross
Employment - Foundation Medicine
 
Philip J. Stephens
Employment - Foundation Medicine
 
Vincent A. Miller
Employment - Foundation Medicine
Leadership - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
Patents, Royalties, Other Intellectual Property - Receive periodic royalties related to T790M patent awarded to Memorial Sloan Kettering Cancer Center
 
Siraj Mahamed Ali
Employment - Foundation Medicine; Foundation Medicine
Stock and Other Ownership Interests - Agios; Blueprint Medicines; Exelixis
Patents, Royalties, Other Intellectual Property - patents via FOundation Medicine; Patents via Seres Health on microbiome stuff in non neoplastic disease (I)
 
Alexa Betzig Schrock
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine