The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase Ib open-label, dose escalation and expansion study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK525762 in combination with abiraterone or enzalutamide in metastatic castrate-resistant prostate cancer.
 
Ulka N. Vaishampayan
Honoraria - Astellas Pharma; Bayer; Bristol-Myers Squibb; Exelixis; Genentech; Janssen; Novartis; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; Bayer; Bristol-Myers Squibb; Exelixis; Genentech/Roche; Pfizer
Speakers' Bureau - Astellas Pharma; Bayer; Bristol-Myers Squibb; Exelixis; Genentech/Roche; Pfizer
Research Funding - Astellas Pharma; Bristol-Myers Squibb; Exelixis; Novartis; Pfizer
 
Vivek Narayan
Research Funding - Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst)
 
David Wise
No Relationships to Disclose
 
Joshua Michael Lang
Stock and Other Ownership Interests - Salus Discovery
Consulting or Advisory Role - Sanofi; Sanofi
Research Funding - Agensys (Inst); Medivation (Inst); Novartis (Inst)
Patents, Royalties, Other Intellectual Property - I am listed on the patent on a technology for rare cell capture and analysis. This technology has been licensed by Salus Discovery, LLC though no commercial products are available.
 
Benjamin H Lowentritt
Consulting or Advisory Role - Astellas Medivation; Bayer; Dendreon; Janssen
Speakers' Bureau - Bayer; Dendreon; Janssen
Research Funding - Astellas Pharma (Inst); Bayer (Inst); Innocrin Pharma (Inst); Janssen (Inst)
 
Begona Mellado
Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Janssen; Pfizer; Roche
Research Funding - Astellas Pharma (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Janssen; Pfizer
 
Joan Carles
Consulting or Advisory Role - Astellas Pharma; Bayer; Bristol-Myers Squibb; Johnson & Johnson; Pfizer; Sanofi
Speakers' Bureau - Bayer; Johnson & Johnson
 
M Isabel Sáez
Consulting or Advisory Role - Astellas Pharma; Janssen; Sanofi
 
Wassim Abida
Honoraria - CARET
Consulting or Advisory Role - Clovis Oncology
Research Funding - AstraZeneca; Clovis Oncology; Zenith Epigenetics
 
Mary-Ellen Taplin
Honoraria - Bayer; Clovis Oncology; Janssen-Ortho; Medivation
Consulting or Advisory Role - Bayer; Best Doctors, Inc; Clovis Oncology; Dava Oncology; Guidepoint Global; Janssen-Ortho; Medivation; Myovant Sciences; Research to Practice; Sanofi; UpToDate
Research Funding - Bayer (Inst); Genentech (Inst); Janssen-Ortho (Inst); Medivation (Inst); Tokai Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - Janssen Oncology; Medivation; Tokai Pharmaceuticals
 
Arun Azad
Honoraria - Astellas Pharma; Janssen; Novartis
Consulting or Advisory Role - Astellas Pharma; Novartis
Speakers' Bureau - Janssen
Research Funding - Astellas Pharma
Travel, Accommodations, Expenses - Astellas Pharma
 
Karrie Wang
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Olena Barbash
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Geraldine Ferron-Brady
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
 
Doug Fecteau
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - GlaxoSmithKline
Travel, Accommodations, Expenses - Merck
 
Ahmed Hussein Khaled
Employment - GlaxoSmithKline
 
Arindam Dhar
Employment - GlaxoSmithKline
Stock and Other Ownership Interests - Bristol-Myers Squibb; GlaxoSmithKline
Travel, Accommodations, Expenses - GlaxoSmithKline
 
Johann S. De Bono
Honoraria - Astellas Pharma; AstraZeneca; Genentech/Roche; Pfizer; Sanofi
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Genentech/Roche; Sanofi
Research Funding - AstraZeneca (Inst); Genentech (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); PARP inhibitors and DNA repair defects (Inst)
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex