The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1b/2 study of CPI-1205, a small molecule inhibitor of EZH2, combined with enzalutamide (E) or abiraterone/prednisone (A/P) in patients with metastatic castration resistant prostate cancer (mCRPC).
 
Mary-Ellen Taplin
Honoraria - Bayer; Clovis Oncology; Janssen-Ortho; Medivation
Consulting or Advisory Role - Bayer; Best Doctors, Inc; Clovis Oncology; Dava Oncology; Guidepoint Global; Janssen-Ortho; Medivation; Myovant Sciences; Research to Practice; Sanofi; UpToDate
Research Funding - Bayer (Inst); Genentech (Inst); Janssen-Ortho (Inst); Medivation (Inst); Tokai Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - Janssen Oncology; Medivation; Tokai Pharmaceuticals
 
Arif Hussain
Consulting or Advisory Role - AstraZeneca; Bayer; Bristol-Myers Squibb; Novartis
Research Funding - Agensys; Bayer; Cerulean Pharma; Clovis Oncology; Merck; Sotio
 
Neal D. Shore
Leadership - Large Urology Group Practice Association
Consulting or Advisory Role - Amgen; AstraZeneca; Bayer; Dendreon; Ferring; Genentech/Roche; Janssen Scientific Affairs; Medivation/Astellas; Myovant Sciences; Pfizer; Sanofi; Tolmar
 
Bill Bradley
Employment - Constellation Pharmaceuticals
Stock and Other Ownership Interests - Constellation Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Constellation Pharmaceuticals
 
Patrick Trojer
Employment - Constellation Pharmaceuticals
Leadership - Constellation Pharmaceuticals
Stock and Other Ownership Interests - Constellation Pharmaceuticals
 
Claudia Lebedinsky
Employment - Constellation Pharmaceuticals; Shire
Stock and Other Ownership Interests - Constellation Pharmaceuticals; Shire
 
Adrian Mario Senderowicz
Employment - Constellation Pharmaceuticals; Puma Biotechnology
Leadership - Constellation Pharmaceuticals; Puma Biotechnology
Stock and Other Ownership Interests - Constellation Pharmaceuticals; Puma Biotechnology
Consulting or Advisory Role - Puma Biotechnology
Travel, Accommodations, Expenses - Puma Biotechnology
 
Emmanuel S. Antonarakis
Honoraria - Astellas Pharma; Dendreon; ESSA; Janssen Biotech; Medivation; Sanofi
Consulting or Advisory Role - Astellas Pharma; Dendreon; ESSA; Janssen Biotech; Medivation; Sanofi
Research Funding - Aragon Pharmaceuticals (Inst); Astellas Pharma (Inst); Dendreon (Inst); Exelixis (Inst); Genentech (Inst); Janssen Biotech (Inst); Johnson & Johnson (Inst); Millennium (Inst); Novartis (Inst); Sanofi (Inst); Tokai Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - Dendreon; Medivation; Sanofi