The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase 1 trial of trametinib alone and in combination with dabrafenib in children and adolescents with relapsed solid tumors or neurofibromatosis type 1 (NF1) progressive plexiform neurofibromas (PN).
 
Birgit Geoerger
No Relationships to Disclose
 
Christopher L. Moertel
Employment - Recombinetics
Leadership - OX2 Therapeutics
Stock and Other Ownership Interests - OX2 Therapeutics
Research Funding - Novartis (Inst)
Patents, Royalties, Other Intellectual Property - OX2 Therapeutics
 
James Whitlock
Honoraria - Jazz Pharmaceuticals; Medical Learning Group
Consulting or Advisory Role - Amgen; Amgen; eviti; Gilead Sciences; Janssen-Ortho; Jazz Pharmaceuticals; Shire
Research Funding - GlaxoSmithKline (Inst); GlaxoSmithKline (Inst); Kite, a Gilead company (Inst); Novartis (Inst)
 
Geoffrey Brian McCowage
Research Funding - Epizyme; Merck; Novartis
 
Mark W. Kieran
Consulting or Advisory Role - Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Merck; Novartis; Sigma-Tau; Takeda
Speakers' Bureau - Merck Sharp & Dohme
Travel, Accommodations, Expenses - Merck Sharp & Dohme
 
Alberto Broniscer
No Relationships to Disclose
 
Darren R Hargrave
Consulting or Advisory Role - AstraZeneca; Bayer; Boehringer Ingelheim; Novartis; Roche/Genentech
Research Funding - AstraZeneca
Expert Testimony - AstraZeneca
Travel, Accommodations, Expenses - Boehringer Ingelheim; Novartis; Roche/Genentech
Other Relationship - Abbvie; Bristol-Myers Squibb; Celgene; Novartis
 
Pooja Hingorani
No Relationships to Disclose
 
Lindsay Baker Kilburn
Employment - Kaiser Permanente (I)
Research Funding - Epizyme (Inst); Novartis (Inst)
 
Sabine Mueller
Research Funding - Genentech/Roche
 
Lillian Tseng
Employment - Novartis
Stock and Other Ownership Interests - Novartis
Travel, Accommodations, Expenses - Novartis
 
Noelia Nebot
Employment - Novartis
 
Kohinoor Dasgupta
Employment - Novartis
 
Mark W. Russo
Employment - Novartis
Stock and Other Ownership Interests - GlaxoSmithKline; Novartis
 
Elizabeth Fox
Research Funding - Ignyta (Inst)
Travel, Accommodations, Expenses - Helsinn Therapeutics
Other Relationship - Helsinn Therapeutics