The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Phase ib/2a study of PLX51107, a small molecule BET inhibitor, in subjects with advanced hematological malignancies and solid tumors.
 
Amita Patnaik
Consulting or Advisory Role - Bayer
Research Funding - Abbvie; Aeglea Biotherapeutics; Alexion Pharmaceuticals; Amgen; Asana Biosciences; Ascentage Pharma Group; Astex Pharmaceuticals; AVEO (Inst); Bayer; Bayer (Inst); Calithera Biosciences; Celgene (Inst); Cerulean Pharma (Inst); Corvus Pharmaceuticals (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); Endocyte (Inst); Five Prime Therapeutics (Inst); Formation Biologics (Inst); Forty Seven; Gilead Sciences (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Jiangsu Hengrui Medicine; Jiangsu Hengrui Medicine (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Merck Sharp & Dohme; Novartis; OncoMed; Pfizer (Inst); Plexxikon; Plexxikon (Inst); Regeneron (Inst); Symphony Evolution (Inst); TaiRx, Inc. (Inst); Tesaro (Inst); Tesaro (Inst); Teva (Inst); Upsher-Smith; Zymeworks (Inst)
 
Richard D. Carvajal
Consulting or Advisory Role - AstraZeneca; Aura Biosciences; Bristol-Myers Squibb; Castle Biosciences; Genentech/Roche; Iconic Therapeutics; Janssen Oncology; Merck; Novartis
 
Kimberly Mayumi Komatsubara
Consulting or Advisory Role - Roche
 
Carolyn D. Britten
Consulting or Advisory Role - Cleave Biosciences
Research Funding - Amgen (Inst); AstraZeneca (Inst); Boston Biomedical (Inst); EMD Serono (Inst); Five Prime Therapeutics (Inst); Halozyme (Inst); Incyte (Inst); Keystone Nano (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst); Plexxikon (Inst); RedHill Biopharma (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Five Prime Therapeutics
 
Robert Wesolowski
Consulting or Advisory Role - Agenus; Novartis; Pfizer (Inst)
Research Funding - Acerta Pharma
Travel, Accommodations, Expenses - Agenus; Novartis; Pfizer
 
Glenn Michelson
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Oscar Alcantar
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Chao Zhang
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Ben Powell
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Paul Severson
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Eric Martin
Employment - Plexxikon
Stock and Other Ownership Interests - Plexxikon
 
Marlana M. Orloff
Consulting or Advisory Role - Castle Biosciences
Research Funding - Bristol-Myers Squibb (Inst)