The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Results of the first-in-human study of ABBV-075 (mivebresib), a pan-inhibitor of bromodomain (BD) and extra terminal (BET) proteins, in patients (pts) with relapsed/refractory (R/R) solid tumors.
 
Sarina Anne Piha-Paul
Consulting or Advisory Role - Genentech
Research Funding - Abbvie; Bayer; BlueLink; Curis; Five Prime Therapeutics; GlaxoSmithKline; Helix BioPharma; Incyte; MedImmune; Medivation; Merck Sharp & Dohme; Novartis; Pfizer; Pieris Pharmaceuticals; Principa Biopharma; Puma Biotechnology; Tesaro; XuanZhu
 
Jasgit C. Sachdev
Honoraria - Celgene
Consulting or Advisory Role - Celgene
Research Funding - Celgene (Inst)
Travel, Accommodations, Expenses - Celgene
 
Minal A. Barve
No Relationships to Disclose
 
Patricia LoRusso
Leadership - Agios; Five Prime Therapeutics; Halozyme; Roche/Genentech
Honoraria - Genentech/Roche
Consulting or Advisory Role - Alexion Pharmaceuticals; ARIAD; CytomX Therapeutics; Genentech; Genentech; Genmab; Glenmark; Ignyta; Menarini; Novartis; Omniox; Takeda
Research Funding - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech (Inst); Immunogen (Inst); Merrimack (Inst); Novartis (Inst); Pfizer; Taiho Pharmaceutical (Inst); Tensha Therapeutics (Inst)
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Genentech/Roche
 
Russell Zelig Szmulewitz
Consulting or Advisory Role - Abbvie; Amgen; AstraZeneca; Exelixis; Janssen Oncology; Merck
Research Funding - Abbvie; Astellas Pharma; Incyte; Janssen Oncology; Macrogenics
Patents, Royalties, Other Intellectual Property - Patent licensed by University of Chicago of which I am co-inventor to Corcept Therapeutics for combination AR/GR inhibition in prostate cancer
Travel, Accommodations, Expenses - Corcept Therapeutics
 
Sapna Pradyuman Patel
Stock and Other Ownership Interests - Provectus
Honoraria - PCME, Rockpointe; Society for Immunotherapy of Cancer
Consulting or Advisory Role - Cardinal Health; Castle Biosciences; Incyte
Research Funding - Bristol-Myers Squibb (Inst); Celgene (Inst); Deciphera (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Provectus (Inst); Reata Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - Cardinal Health; Castle Biosciences; Incyte; Massachusetts General Hospital; PCME, Rockpointe; Socrates Analytics
 
Mark D. McKee
Employment - AbbVie
Stock and Other Ownership Interests - AbbVie
 
Johannes E. Wolff
Employment - AbbVie
Stock and Other Ownership Interests - AbbVie
Travel, Accommodations, Expenses - AbbVie
 
Beibei Hu
Employment - Abbvie
Stock and Other Ownership Interests - Abbvie
Travel, Accommodations, Expenses - Abbvie
 
Anjla Sood
Employment - AbbVie
Stock and Other Ownership Interests - Abbvie; Abbvie (I)
Honoraria - QOL Medical LLC (I); Sucampo Pharmaceuticals (I)
Consulting or Advisory Role - Kimberly-Clark (I); QOL Medical LLC (I); Sucampo Pharmaceuticals (I); Takeda (I)
 
Xiaotian Chen
Employment - Abbvie
Travel, Accommodations, Expenses - Abbvie
 
Sarah C. Wilson
Employment - Abbvie
Stock and Other Ownership Interests - Abbott
Travel, Accommodations, Expenses - AbbVie
 
Bert H. O'Neil
Consulting or Advisory Role - Amgen; Bayer; Bristol-Myers Squibb; Genentech/Roche; Halozyme
Speakers' Bureau - Celgene
Travel, Accommodations, Expenses - Bayer; Merck KGaA