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Overall survival (OS) update of the double-blind placebo (PBO)-controlled randomized phase 2 LOTUS trial of first-line ipatasertib (IPAT) + paclitaxel (PAC) for locally advanced/metastatic triple-negative breast cancer (mTNBC). |
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No Relationships to Disclose |
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Consulting or Advisory Role - AstraZeneca; Hanmi; Novartis; Pfizer; Roche |
Research Funding - AstraZeneca (Inst) |
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Travel, Accommodations, Expenses - Novartis |
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Employment - University of Washington (I) |
Leadership - Northwest Medical Specialties |
Stock and Other Ownership Interests - Northwest Medical Specialties |
Consulting or Advisory Role - Bristol-Myers Squibb |
Research Funding - Northwest Medical Specialties |
Expert Testimony - Northwest Medical Specialties |
Travel, Accommodations, Expenses - Northwest Medical Specialties |
Other Relationship - All4Cure (I); Northwest Medical Specialties; Quality Cancer Care Alliance |
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Consulting or Advisory Role - Abbvie |
Research Funding - Abbvie (Inst); Advaxis (Inst); Bayer/Onyx (Inst); Eisai (Inst); Genentech (Inst); GlaxoSmithKline (Inst); MedImmune (Inst); Merck (Inst); Pfizer (Inst); Tesaro (Inst) |
Travel, Accommodations, Expenses - Caris Centers of Excellence; Caris Life Sciences |
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Consulting or Advisory Role - Abbvie; Genentech/Roche; PharmaMar |
Research Funding - Abbvie (Inst); AstraZeneca/MedImmune (Inst); Genentech (Inst); Merck (Inst); OncoPep (Inst); PharmaMar (Inst) |
Travel, Accommodations, Expenses - PharmaMar |
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Consulting or Advisory Role - Roche/Genentech |
Research Funding - AstraZeneca (Inst); Genentech/Roche (Inst) |
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Consulting or Advisory Role - Pfizer; Puma Biotechnology; Roche |
Research Funding - AstraZeneca (Inst); Genentech (Inst) |
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Employment - Genentech/Roche |
Stock and Other Ownership Interests - ARIAD; Genentech/Roche |
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Employment - Genentech/Roche; Genentech/Roche (I) |
Stock and Other Ownership Interests - Roche; Roche (I) |
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Employment - BeiGene; Genentech |
Stock and Other Ownership Interests - Genentech |
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No Relationships to Disclose |
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Employment - Roche/Genentech |
Stock and Other Ownership Interests - Roche/Genentech |
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Leadership - Infinity Pharmaceuticals; Varian Medical Systems |
Stock and Other Ownership Interests - GRAIL; Infinity Pharmaceuticals; Juno Therapeutics; PMV Pharma; Varian Medical Systems |
Consulting or Advisory Role - GRAIL; Lilly; Novartis |
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Research Funding - Dongkook (Inst); Novartis (Inst); Samyang (Inst); Sanofi (Inst) |