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A phase 1, open-label, multicenter, non-randomized study to assess the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of AZD4573, a potent and selective CDK9 inhibitor, in subjects with relapsed or refractory hematological malignancies. |
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No Relationships to Disclose |
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Consulting or Advisory Role - Abbvie; Celgene; Janssen Oncology; Sunesis Pharmaceuticals |
Research Funding - Celgene (Inst); Gilead Sciences (Inst); Janssen Oncology (Inst); Roche Pharma AG (Inst); Sanofi (Inst) |
Travel, Accommodations, Expenses - Abbvie |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Honoraria - Amgen; Celgene; Takeda |
Consulting or Advisory Role - Amgen; Celgene; Janssen Oncology |
Research Funding - Celgene (Inst); Janssen Oncology (Inst) |
Travel, Accommodations, Expenses - Takeda |
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No Relationships to Disclose |
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Consulting or Advisory Role - Abbvie; Amgen; AstraZeneca; Celgene; Gilead Sciences; GlaxoSmithKline; Janssen Oncology; Novartis; Roche Pharma AG |
Research Funding - Abbvie (Inst); Amgen (Inst); Celgene (Inst); Gilead Sciences (Inst); Janssen Oncology (Inst); Roche Pharma AG (Inst) |
Travel, Accommodations, Expenses - Abbvie; Amgen; AstraZeneca; Celgene; Gilead Sciences; Janssen Oncology; Novartis; Roche Pharma AG |
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No Relationships to Disclose |
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Honoraria - Abbvie/Genentech; Roche Pharma AG; Sandoz |
Speakers' Bureau - Roche Pharma AG |
Research Funding - Astex Pharmaceuticals (Inst); Bioinvent (Inst); Gilead Sciences (Inst); Roche Pharma AG (Inst) |
Travel, Accommodations, Expenses - Abbvie/Genentech |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - AstraZeneca |
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Stock and Other Ownership Interests - AstraZeneca |
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No Relationships to Disclose |
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Honoraria - Gilead Sciences; Janssen Oncology; Roche Pharma AG |
Consulting or Advisory Role - Celgene; Gilead Sciences; Roche/Genentech; Takeda |
Research Funding - Acerta Pharma (Inst); Celgene (Inst); Gilead Sciences (Inst); Janssen Oncology (Inst); Roche Pharma AG (Inst); Takeda (Inst) |
Travel, Accommodations, Expenses - Celgene; Gilead Sciences; Roche Pharma AG; Takeda |
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Stock and Other Ownership Interests - AstraZeneca |
Travel, Accommodations, Expenses - AstraZeneca |