The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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SPIRE: A phase Ib/randomised IIa open label clinical trial combining guadecitabine (SGI-110) with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer.
 
Simon J. Crabb
Honoraria - Janssen-Cilag; Novartis; Roche
Consulting or Advisory Role - Bayer; Clovis Oncology; Janssen-Cilag; Roche
Research Funding - Astex Pharmaceuticals; AstraZeneca; Clovis Oncology; Plexxikon
Travel, Accommodations, Expenses - Bayer; Bristol-Myers Squibb; Ipsen; Janssen-Cilag; Merck; Roche
 
Sarah Danson
Consulting or Advisory Role - Inca Pharma
Speakers' Bureau - Amgen; Bristol-Myers Squibb
Research Funding - Amgen (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Lilly (Inst); MSD (Inst); Sierra Oncology (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD
 
James Catto
Honoraria - Abbott Laboratories
Speakers' Bureau - ASCO
Travel, Accommodations, Expenses - European Association of Urology
 
Cathy McDowell
No Relationships to Disclose
 
Denise Dunkley
Employment - Abbvie (I)
Leadership - Abbvie (I)
Stock and Other Ownership Interests - Abbvie (I)
 
Robert A Huddart
Leadership - Cancer clinic london Limited liability partnership
Honoraria - Janssen Oncology
Consulting or Advisory Role - Bristol-Myers Squibb; Merck Sharp & Dohme; Roche
Speakers' Bureau - AstraZeneca; Pierre Fabre
Research Funding - Active Biotech; Bristol-Myers Squibb (Inst); Ipsen; Merck Sharp & Dohme (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Janssen Oncology; MSD Oncology; Roche/Genentech
 
Gareth Griffiths
No Relationships to Disclose