The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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First-in-human phase 1 study of the PARP/tankyrase inhibitor 2X-121 (E7449) as monotherapy in patients with advanced solid tumors and validation of a novel drug response predictor (DRP) mRNA biomarker.
 
Elizabeth Ruth Plummer
Honoraria - Bristol-Myers Squibb; Pfizer (I); Roche/Genentech
Consulting or Advisory Role - Astex Pharmaceuticals; Bayer; Clovis Oncology; Modulatex; MSD Oncology; Novartis; Octimet; Pierre Fabre; Roche/Genentech; Vertex
Speakers' Bureau - Novartis
Research Funding - AstraZeneca/MedImmune (Inst)
Patents, Royalties, Other Intellectual Property - Named on patent of use of PARP inhibitor rucaparib (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD Oncology
 
Divyanshu Dua
No Relationships to Disclose
 
Nicola Cresti
No Relationships to Disclose
 
Aneta Suder
Honoraria - Pfizer
Travel, Accommodations, Expenses - Astellas Oncology
 
Yvette Drew
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Clovis Oncology
Speakers' Bureau - AstraZeneca
Research Funding - Clovis Oncology (Inst); Verastem (Inst)
Travel, Accommodations, Expenses - Clovis Oncology
 
Peter Stephens
No Relationships to Disclose
 
Marie Foegh
Employment - 2X Oncology
Leadership - 2X Oncology
Stock and Other Ownership Interests - Agile Therapeutics
Consulting or Advisory Role - 2X Oncology
Patents, Royalties, Other Intellectual Property - Agile Therapeutics
 
Steen Knudsen
Employment - Medical Prognosis Institute
Leadership - Medical Prognosis Institute
 
Sharon McGonigle
Employment - Eisai
 
Barbara Ink
Employment - Eisai
Leadership - Eisai
 
Debashis Sarker
Honoraria - Bayer; Ipsen; Pfizer; Pfizer (I)
Consulting or Advisory Role - Baxalta; Blueprint Medicines; Eisai; Eisai (I); Ipsen (I); Novartis
Travel, Accommodations, Expenses - Bayer; ipsen; MiNA Therapeutics