The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1a / 1b first-in-human, open-label, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of oral TP-0903, a potent inhibitor of AXL kinase, administered daily for 21 days to patients with advanced solid tumors.
 
John Sarantopoulos
Consulting or Advisory Role - Amgen; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Eisai; Exelixis; Fulgent Genetics; Genentech/Roche; Merck; Novartis; Pfizer; Sun Pharma; Takeda
 
Muhammad Shaalan Beg
Consulting or Advisory Role - Celgene; Genentech/Roche; Guardant Health; Ipsen; Merrimack
Speakers' Bureau - Genentech/Roche; Ipsen
Research Funding - Agios (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Merck Serono (Inst)
 
Georgios Fotopoulos
No Relationships to Disclose
 
Josephine Amalia Taverna
No Relationships to Disclose
 
Stephen P. Anthony
Employment - Amgen; Tolero Pharmaceuticals
Stock and Other Ownership Interests - Amgen
Honoraria - AstraZeneca
Consulting or Advisory Role - Paradigm; Zymeworks
Travel, Accommodations, Expenses - AstraZeneca
 
Steven D. Weitman
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Stock and Other Ownership Interests - miRNA Therapeutics; Tolero Pharmaceuticals
Consulting or Advisory Role - Cytori Therapeutics; Kinex; miRNA Therapeutics; Sanofi; Shire; Sunesis Pharmaceuticals
Travel, Accommodations, Expenses - Kinex; Tolero Pharmaceuticals
 
Steven L Warner
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Stock and Other Ownership Interests - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Inventor and royalty recipient for patent covering TP-0903
 
Lars Mouritsen
Employment - Sorrento Therapeutics; Tolero Pharmaceuticals
Leadership - Sorrento Therapeutics
Stock and Other Ownership Interests - Sorrento Therapeutics
 
David Bearss
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Stock and Other Ownership Interests - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Patents
 
Susan Smith
No Relationships to Disclose
 
Holly Beever
No Relationships to Disclose
 
Vivek Khemka
Employment - Cancer Treament Centers of America
Research Funding - Acerta Pharma (Inst); AstraZeneca/MedImmune (Inst); Caris Centers of Excellence (Inst); Caris Life Sciences (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Jiangsu Hengrui Medicine (Inst); Plexxikon (Inst); Tesaro (Inst); Tolero Pharmaceuticals (Inst); Toray Industries (Inst)