The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Impact of MLH1, PMS2, MSH2, and MSH6 alterations on tumor mutation burden (TMB) and PD-L1 expression in 1,057 microsatellite instability-high (MSI-H) tumors.
 
Mohamed E. Salem
Consulting or Advisory Role - Genentech/Roche; Taiho Pharmaceutical
Speakers' Bureau - Genentech/Roche; Taiho Pharmaceutical
Research Funding - Bayer (Inst); Taiho Pharmaceutical (Inst)
 
Axel Grothey
Consulting or Advisory Role - Amgen (Inst); Array BioPharma (Inst); Bayer (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); Guardant Health (Inst); Lilly (Inst)
Research Funding - Bayer (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Eisai (Inst); Genentech/Roche (Inst); Lilly (Inst); Pfizer (Inst); Sanofi (Inst)
Travel, Accommodations, Expenses - Amgen; Bayer; Boehringer Ingelheim; Boston Biomedical; Bristol-Myers Squibb; Genentech/Roche; Merck Sharp & Dohme
 
Edward S. Kim
Honoraria - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
 
Joanne Xiu
Employment - Caris Life Sciences
 
Richard M. Goldberg
Honoraria - Baxter; Biothera; Forty Seven; Immunocare Therapies; kanghong Pharma; Merck; Merck KGaA; Merrimack; Pfizer; Taiho Pharmaceutical; Targovax
Research Funding - Bristol-Myers Squibb (Inst); Merck (Inst); Sanofi (Inst)
Travel, Accommodations, Expenses - Amgen; Baxter; Merck KGaA; Sanofi
 
Wolfgang Michael Korn
Stock and Other Ownership Interests - OncoCyte
Honoraria - Genentech/Roche
Consulting or Advisory Role - Merck Sharp & Dohme; Merrimack
Research Funding - Merrimack (Inst)
Patents, Royalties, Other Intellectual Property - Exelixis
Travel, Accommodations, Expenses - Merrimack
 
Anthony Frank Shields
Employment - Benchling (I)
Stock and Other Ownership Interests - Benchling (I)
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Endocyte; GE Healthcare; Merck; Merrimack; Personal Genome Diagnostics; Siemens Healthcare Diagnostics; Taiho Pharmaceutical
Speakers' Bureau - GE Healthcare
Research Funding - Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Caris Life Sciences; Eisai; H3 Biomedicine; Inovio Pharmaceuticals; Karyopharm Therapeutics; Merrimack; Novartis; OncoMed; Plexxikon; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Caris Life Sciences; Endocyte; GE Healthcare; Merrimack
 
Andreas Seeber
No Relationships to Disclose
 
Jimmy J. Hwang
Consulting or Advisory Role - Amgen; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech/Roche; Ipsen; Taiho Pharmaceutical
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Celgene; Genentech/Roche; Ipsen; Ipsen
Expert Testimony - Roche
 
Philip Agop Philip
Honoraria - Amgen; Bayer; Bristol-Myers Squibb; Celgene; Halozyme; Ipsen; Merck; Novartis; Rafael Pharmaceuticals; Sanofi
Consulting or Advisory Role - Celgene; Gilead Sciences; Halozyme; Ipsen; Merck; Merrimack; novartis
Speakers' Bureau - Bayer; Bristol-Myers Squibb; Celgene; Ipsen; Merck
Research Funding - Bayer (Inst); Genentech (Inst); Immunomedics (Inst); incyte (Inst); Karyopharm Therapeutics (Inst); Merck (Inst); Momenta Pharmaceuticals (Inst); novartis (Inst); Plexxikon (Inst); Regeneron (Inst); Taiho Pharmaceutical (Inst)
Other Relationship - Halozyme
 
Heinz-Josef Lenz
Honoraria - Bayer; Boehringer Ingelheim; Merck Serono; Roche
Consulting or Advisory Role - Bayer; Merck Serono; Pfizer; Roche
Travel, Accommodations, Expenses - Bayer; Merck Serono; Roche
 
Derek Raghavan
Consulting or Advisory Role - Caris Life Sciences (Inst); Gerson Lehrman Group
 
John Marshall
Employment - Caris Life Sciences
Honoraria - Amgen; Bayer/Onyx; Caris Life Sciences; Celgene; Genentech/Roche; Taiho Pharmaceutical
Consulting or Advisory Role - Amgen; Bayer/Onyx; Caris Life Sciences; Celgene; Genentech/Roche; Taiho Pharmaceutical
Speakers' Bureau - Amgen; Bayer/Onyx; Celgene; Genentech/Roche; Taiho Pharmaceutical
Research Funding - Amgen (Inst); Bayer/Onyx (Inst); Boehringer Ingelheim (Inst); Genentech/Roche (Inst); MedImmune (Inst); Pfizer (Inst)